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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Release info for hum0197

  • hum0197-v31

    2026-07-31
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood cells of multiple sclerosis (MS) patients and conrols (688 MS patients and 205,199 controls in the Japanese population, 27,572 MS patients and 1,436,801 controls in the European population, 819 MS patients and 155,904 controls in the African population, and 29,374 MS patients and 1,843,563 controls in the cross-population (293 MS patients and 45,569 controls in the US population was included).) were genotyped and performed genome-wide association study. A tsv file is provided.
    - RNAs extracted from PBMCs of 20 MS patients were subjected to single-cell RNA-seq analysis. Integrated data are provided (h5ad file).

  • hum0197-v30

    2026-03-10
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood cells of 401 patients with moyamoya disease and 47,255 controls were genotyped and performed genome-wide association study. A text file is provided.

  • hum0197-v29

    2026-01-22
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood cells of 1,434 patients with myasthenia gravis and 42,913 controls were genotyped, imputed, and genome-wide association study was performed (text file).

  • hum0197-v28

    2025-12-12
    Datasets added in this release
    Release note
    - RNAs extracted from PBMC of 3 Japanese male asthma patients were used to RNA-seq analysis. Fastq files are provided.
    - DNAs/RNAs extracted from PBMC of 4 Japanese male COVID-19 patients were used to snMultiome (snRNA+snATAC) analysis. Fastq files are provided.

  • hum0197-v27

    2025-12-02
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood of 161,026 Japanese males were used for whole genome sequencing. The genome-wide association study summary statistics for the detected variants will be provided in a text file.

  • hum0197-v26

    2025-10-27
    Datasets added in this release
    Release note
    DNAs extracted from the Japanese (BioBank Japan; N = 166,757) and British (UK Biobank; N = 273,453) populations were genotyped, imputed and genome-wide association analysis for 374 phenotypes focusing gene-environment interactions. The genome-wide association study summary statistics for the detected variants will be provided in a text file.

  • hum0197-v25

    2025-07-25
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood of patients with 1,415 psoriasis patients and 3,968 controls were used for whole genome sequencing. The genome-wide association study summary statistics for the detected variants will be provided in a text file.

  • hum0197-v24

    2025-05-07
    Datasets added in this release
    Release note
    - Single-cell eQTL summary statistics for 40 immune cell types using scRNA-seq analysis data from 234 Japanese individuals (88 COVID-19 cases and 146 healthy controls) and plasma proteome data (matrix data for each subject x each protein) from 227 individuals (83 COVID-19 cases and 144 healthy controls) are provided as text files.
    - RNAs extracted from PBMCs of 87 Japanese individuals (15 COVID-19 patients and 72 healthy controls) were subjected to single-cell RNA-seq analysis. Fastq files are provided.

  • hum0197-v23

    2024-12-18
    Datasets added in this release
    Release note
    - DNAs extracted from peripheral blood of patients with 240 NMOSD patients and 50,578 controls were used for whole genome sequencing. Summary statistics of the genome-wide meta-analysis performed on WGS are provided (txt file).
    - RNAs extracted from PBMCs of NMOSD patients were subjected to single-cell RNA-seq analysis. Integrated data are provided (rds file).

  • hum0197-v22

    2024-11-11
    Datasets added in this release
    Release note
    - DNAs extracted from tumor tissues and blood samples of 14 HPV-associated oropharyngeal cancer patients were subjected to whole-genome sequencing. Fastq files are provided.
    - RNAs extracted from tumor tissues of 19 HPV-associated oropharyngeal cancer patients and 17 Non-HPV-associated oropharyngeal cancer patients and normal tonsils of two healthy controls were subjected to bulk RNA sequencing. Fastq files are provided.

  • hum0197-v21

    2024-10-28
    Datasets added in this release
    Release note
    - DNAs extracted from peripheral blood of patients with autoimmune diseases and control participants were used for whole genome sequencing. The presence or absence of endogenous herpesvirus 6 and anellovirus load calculated from WGS are provided (tsv file).
    - DNAs extracted from peripheral blood cells of patients with eHHV-6B-positive/-negative autoimmune diseases were genotyped, imputed, and genome-wide association study was performed (tsv file).
    - RNAs extracted from PBMCs of eHHV-6B-positive/-negative SLE patients were subjected to single-cell RNA-seq analysis. (fastq files).
    - DNAs extracted from the Japanese populations were genotyped, imputed, and genome-wide association study for the individual Jomon proportions was performed (text file).

  • hum0197-v20

    2024-05-30
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood cells of patients with recurrent pregnancy loss were genotyped, imputed, and genome-wide association study was performed (text file).

  • hum0197-v19

    2024-05-29
    Datasets added in this release
    Release note
    The weights of variants existing in the target cohorts, Tohoku Medical Megabank and the second cohort of BBJ, were calculated from GWAS results on 27,642 type 2 diabetes cases and 70,242 controls from BioBank Japan and 27,642 type 2 diabetes cases and 70,242 controls from UK Biobank (text file).

  • hum0197-v18

    2023-10-02
    Datasets added in this release
    Release note
    DNAs extracted from the Japanese populations were genotyped, imputed, and genome-wide association studies for gut microbiome, plasma metabolite, KEGG Gene Ortholog and KEGG Pathway were performed (text file).

  • hum0197-v17

    2023-06-27
    Datasets added in this release
    Release note
    DNAs extracted from peripheral blood cells of patients with Hunner-type interstitial cystitis were genotyped, imputed, and genome-wide association study was performed (text file).

  • hum0197-v16

    2023-06-06
    Datasets added in this release
    Release note
    DNAs extracted from the Japanese and trans-ethnic populations were genotyped, imputed, and genome-wide association studies and meta analyses for 15 phenotypes were performed (text file).

  • hum0197-v15

    2023-03-29
    Datasets added in this release
    Release note
    Metagenome analyses of the gut microbiome in the Japanese population and healthy individuals were performed by utilizing whole-genome shotgun sequencing. Fastq files are provided.
    - Shotgun sequencing data for 88 Japanese individuals
    - Shotgun sequencing data for 73 healthy individuals (DNA extraction was performed with phenol-chloroform extraction). Among these individuals, 47 were also subjected to DNA extraction with DNeasy PowerSoil Pro kit and sequenced.
    - Deep shotgun sequencing data for 5 Japanese individuals

  • hum0197-v14

    2023-02-16
    Datasets added in this release

    No datasets were added.

    Release note
    DNAs extracted from the Japanese and trans-ethnic populations were genotyped, imputed, and genome-wide association studies and meta analyses for 5 phenotypes were performed (text file).

  • hum0197-v13

    2023-02-14
    Datasets added in this release
    Release note
    RNAs extracted from PBMCs of 43 COVID-19 patients and 44 healthy controls were subjected to single-cell RNA-seq analysis. Fastq files are provided. Clinical data for hum0197.v11 and hum0197.v13 are provided as xlsx files.

  • hum0197-v12

    2022-12-01
    Datasets added in this release
    Release note
    Assembled microbial genome sequences obteined from metagenome analysis at hum0197.v7 and hum0197.v8 are provided (fasta files).

  • hum0197-v11

    2022-07-21
    Datasets added in this release
    Release note
    RNAs extracted from PBMCs of 30 COVID-19 patients and 31 healthy controls were subjected to single-cell RNA-seq analysis. Fastq files are provided.

  • hum0197-v10

    2022-06-16
    Datasets added in this release
    Release note
    DNAs extracted from the Japanese and British populations were genotyped, imputed, genome-wide association studies, and meta analyses for 9 phenotypes were performed (text file).

  • hum0197-v9

    2022-06-10
    Datasets added in this release
    Release note
    DNAs extracted from patients with intracranial germ cell tumors were genotyped, imputed, and performed a genome-wide association study (text file).

  • hum0197-v8

    2022-06-03
    Datasets added in this release
    Release note
    Metagenome analysis of the gut microbiome in the Japanese population was performed by utilizing whole-genome shotgun sequencing. Fastq files are provided.

  • hum0197-v7

    2022-05-23
    Datasets added in this release
    Release note
    A metagenome-wide association study of gut microbiome in Inflammatory Bowel Disease (35 Ulcerative Colitis and 39 Crohn's disease) and 40 Healthy controls was performed by utilizing whole-genome shotgun sequencing. Fastq files are provided.

  • hum0197-v6

    2022-02-08
    Datasets added in this release
    Release note
    - RNAs extracted from PBMCs of 141 Japanese individuals were subjected to small RNA-seq analysis. Read count data of miRNAs is provided as a txt file.
    - gDNAs extracted from whole blood of 141 Japanese individuals were subjected to whole genome sequencing analysis. miRNA-eQTL mapping was performed. eQTL summary data is provided as a txt file.

  • hum0197-v5

    2021-12-21
    Datasets added in this release
    Release note
    - DNAs extracted from the Japanese populations were genotyped, imputed, and genome-wide association study for 10 phenotypes were performed (text file).
    - DNAs extracted from the Japanese populations were genotyped, imputed, and fine-mapping study for 79 phenotypes were performed (text file).

  • hum0197-v4

    2021-12-10
    Datasets added in this release
    Release note
    A metagenome-wide association study of gut microbiome in the Japanese population was performed by utilizing whole-genome shotgun sequencing. Fastq files are provided.

  • hum0197-v3

    2021-03-22
    Datasets added in this release
    Release note
    DNAs extracted from the Japanese and trans-ethnic populations were genotyped, imputed, and genome-wide association studies and meta analyses for 215 phenotypes were performed (text file).

  • hum0197-v2

    2020-11-27
    Datasets added in this release
    Release note
    - DNAs extracted from autoimmune pulmonary alveolar proteinosis patients were genotyped, imputed, and genome-wide association study was performed (text file).
    - A metagenome-wide association study of gut microbiome in the Japanese population was performed by utilizing whole-genome shotgun sequencing. Fastq files are provided.

  • hum0197-v1

    2019-11-15
    Datasets added in this release
    Release note
    A metagenome-wide association study of gut microbiome in the Japanese population was performed by utilizing whole-genome shotgun sequencing. Fastq files are provided.