5' and 3' single-cell RNA-seq, Micro-C and Region Capture Micro-C, CITE-seq and 5' single-cell RNA-seq, Multimodal assay including single-nucleus ATAC-seq, 3' and 5' single-nucleus RNA-seq, and 5' single-cell RNA-seq, MAS-seq, CAGE-seq, and NET-CAGE-seq were performed on CD4 positive T cells isolated from whole blood of three healthy Japanese. CAGE-seq was performed on CRISPR-activated Jurkat cells. Fastq, bed, matrix, tsv and GTF files are provided.