Proteome data were obtained from serum samples of 3,050 patients from BBJ 1st cohort by Olink Explore3072, Olink Target 96, or Somascan technology. These data were provided in raw_count, csv, adat and pptx files.

Metabolome data was obtained from serum samples of 40,907 patients from BBJ 1st cohort, measured by 500 MHz NMR spectrometers (Bruker AVANCE III HD), and quantified by Nightingale Health's proprietary software (quantification library 2020). These data were provided in xlsx files.

DNAs extracted from the Japanese and trans-ethnic populations were genotyped, imputed, and performed genome-wide association studies and meta-analyses for peptic ulcer disease (text file).

Metabolome data was obtained from serum samples of 2,570 patients from BBJ 1st cohort, measured by 500 MHz NMR spectrometers (Bruker AVANCE III HD), and quantified by Nightingale Health's proprietary software (quantification library 2020). These data were provided in xlsx files.

Metabolome data was obtained from serum samples, measured by 500 MHz NMR spectrometers (Bruker AVANCE IIIHD), and quantified by Nightingale Health's proprietary software (quantification library 2020). These data were provided in xlsx files.

DNAs extracted from peripheral blood cells or saliva of 180,882 patients from BBJ 1st cohort were genotyped by using of Illumina (HumanOmniExpressExome, HumanOmniExpress, HumanExome). Genotype imputation divided into 7 batches was carried out using GenomeStudio Software, Eagle software without a reference panel and Minimac4 software with TOPMed reference panel (Version R2 on GRC38) as a reference. Imputation data and index data were provided in vcf files.

DNAs extracted from peripheral blood cells or saliva of 11,716 patients from BBJ 1st cohort and 42,689 patients from BBJ 2nd cohort were genotyped using Asian Screening Array. Genotyping data of 657,060 variants were provided (idat, csv, plink binary files).