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Dataset ID

JGAD000927

Type of data
Proteome data for 3,050 BBJ participants from BBJ 1st cohort
Access criteria
Controlled-access (Type I)
Total data volume
478 MB
File formats
  • ADAT
  • NPX
  • CSV
  • PPTX
  • TAR
Research
hum0311
Date published
2025-06-13
Date modified
2025-06-13

Analysis method

Proteomics (Olink 2926/1196 + SomaScan 7596 proteins)

Materials and participants
3,050 participants for BBJ 1st cohort (ICD10: C169, C189, C20, C509, C61, I219, L270)
(1) 2,962 participants analyzed at the University of Tokyo
(2) 256 subjects as included in the above 2,962 BBJ 1st participants analyzed at the University of Tokyo
(3) 82 subjects as included in the above 2,962 or 256 BBJ 1st participants analyzed at FonesLife Corporation
(4) another 88 BBJ 1st participant analyzed at Takara Bio Corporation
  • Health status
    Affected
  • Subject count
    3050 (Individual)
  • Cohort
    BioBank Japan
Disease
participants for BBJ 1st cohort (C169, C189, C20, C509, C61, I219, L270)
Sample description
serum samples
  • Tissue
    Serum
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
Proteomics
Target
N/A
Reagent kit
Olink Explore 3072
Olink Target 96
SomaScan
Platform
Olink Explore 3072
Olink Target 96
SomaLogic SomaScan
Normalization
(1) Intensity normalization within each batch, and bridge normalization using 24 samples across 3 batches
(2) Intensity normalization
(3) Adaptive Normalization by Maximum Likelihood (ANML)
(4) Plate normalization
Analysis method
(1) Olink NPX Explore v1.7.1
(2) Olink NPX Signature 1.7.0.0
(3) Detection was conducted by the manufacturer
(4) Olink NPX Explore v1.7.1