Research ID
hum0040-v1Release info
Latest
Research title
Epigenomic analysis of the human placenta
Research overview
- Aims
- Genome-wide identification of parent-of-origin dependent DNA methylation and gene expression in the human placenta
- Methods
- SNPs in human placentas and maternal blood cells were identified using Whole-Genome or Exome sequencing. Allele-specific DNA methylation and gene expression analyses were performed using the human placentas.
- Participants/materials
- Human placentas and maternal blood samples
- URL
- N/A
Datasets
| Cart | Dataset ID | Type of data | Analysis method | Access criteria | Date published |
|---|---|---|---|---|---|
| JGAD000038 | NGS (WGS) NGS (Exome) NGS (WGBS) NGS (RNA-seq) |
| Controlled-access (Type I) | 2020-09-28 |
Data provider
- Principal investigator
- Takahiro Arima
- Affiliation
- Department of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine
Research projects
| Name | URL |
|---|---|
Epigenome Analysis of Cells in the Placenta and Endometrium Forming the Fetal-maternal Interface | N/A |
Grants
| Name | Title | Project number |
|---|---|---|
Core Research and Evolutional Science and Technology, Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-CREST) | Epigenome analysis of cells in the placenta and endometrium forming the fetal-maternal interface |
|
Related publications
| Title | DOI | Dataset ID |
|---|---|---|
Allele-specific methylome and transcriptome analysis reveals widespread imprinting in the human placenta | ||
Derivation of Human Trophoblast Stem Cells |
Controlled access users
| Principal investigator | Affiliation | Country/Region | Research title | Period of data use | Dataset ID |
|---|---|---|---|---|---|
| Martin Hirst | BC Cancer, part of the Provincial Health Services Authority | British Columbia, Canada | Epigenomic analysis of human samples | 2018-08-06 – 2022-09-05 | |
| Zhigang Xue | School of Medicine and Life Science, Tongji University | China | Mechanism of cell programming and embryo-gamete original disease in human embryo development. | 2018-12-17 – 2021-03-19 | |
| Jonghwan Kim | Department of Molecular Biosciences, University of Texas at Austin | Texas, United States | Establishment of human trophoblast stem-like cells derived from human induced pluripotent stem cells for studying human placental development | 2021-05-31 – 2023-07-05 | |
| Gianluca Ursini | Lieber Institute for Brain Development, Johns Hopkins University School of Medicine | Maryland, United States | Analysis of the transcriptional profile of Human Trophoblast Stem Cells | 2022-04-26 – 2026-12-31 | |
| Michiaki Hamada | Hamada Laboratory, Faculty of Science and Engineering, Waseda University | Japan | Construction of RNA-targeted Drug Discovery Database | 2023-01-05 – 2027-10-31 | |
| Masatsugu Ema | Department of Stem Cells and Human Disease Models, Shiga University of Medical Science, Research Center for Animal Life Science | Japan | Isolation and characterization of trophoblast stem cells from human placenta | 2024-08-19 – 2026-08-31 |