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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0567-v1Release info

Latest

Research title

The mutiomics analysis on liver tumor with rare liver diseases, including Fontan associated liver diseases

Research overview

Aims
Most liver cancers develop because of long-term liver disease caused by viruses, drugs, or metabolic disorders. The rare diseases, including Wilson's disease and hemochromatosis also develop liver cancer. Fontan-associated liver disease (FALD) is one of rare diseases and is increasing. Therefore, we conducted a multi-omics analysis targeting liver cancer arising from liver damage caused by rare diseases, especially FALD. This aims to elucidate the causes and development of the disease and establish treatments to improve the prognosis of patients.
Methods
whole-genome sequencing, RNA sequencing
Participants/materials
liver cancer caused by rare liver diseases, especially FALD
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD001048NGS (WGS, RNA-seq)
  • WGS
  • RNA-seq
Controlled-access (Type I)2026-09-24

Data provider

Principal investigator
Tatsuya Kanto
Affiliation
Department of Liver Diseases, The Research Center for Hepatitis and Immunology, National Institute of Global Health and Medicine, Japan Institute for Health Security

Research projects

No research projects.

Grants

NameTitleProject number
Grant-in-Aid for Research, National Center for Global Health and Medicine
Epidemiological and mechanistic studies of FALD for clinical guideline
  • 22A2001
  • 24A2001

Related publications

TitleDOIDataset ID
Genomic and transcriptomic profiling of hepatocellular carcinoma in patients with Fontan-associated liver disease
https://doi.org/10.1097/HEP.0000000000001693 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.