Research ID
hum0416-v1Release info
This page is a past version (v1). The latest version is v5.
Latest version (v5)Research title
Elucidation of biological responses in intractable immune disorders and cancer and development of novel therapies through sequential multilevel omics analysis.
Research overview
- Aims
- In order to grasp the biological reactions and pathological conditions occurring in the body in more detail for diseases involving immune reactions, blood and tissue samples were used and analyzed by following the changes and changes over time for each patient. The present research will acquire and profile comprehensive parameters for each patient and explore factors related to disease conditions and treatments. Then, it will be linked to the understanding of pathology and the development of therapeutic methods through the confirmation of changes in the found molecules and the search for functions.
- Methods
- single-cell CITE-seq (Cellular indexing of transcriptomes and epitopes)
- Participants/materials
- Peripheral blood mononuclear cells (PBMCs) were obtained from blood samples of 8 patients with microscopic polyangiitis (MPA) and 7 healthy donors.
- URL
- N/A
Datasets
The list is the one this version published; each dataset's content is shown as it is now.
| Cart | Dataset ID | Type of data | Analysis method | Access criteria | Date published |
|---|---|---|---|---|---|
| E-GEAD-635 | NGS (CITE-seq) |
| Unrestricted-access | 2023-08-10 |
Data provider
- Principal investigator
- Takehisa Kitazawa
- Affiliation
- Research Division, Chugai Pharmaceutical Co., Ltd.
Research projects
No research projects.
Grants
No grants.
Related publications
| Title | DOI | Dataset ID |
|---|---|---|
Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis |