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NBDC Human Database

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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0379-v1Release info

Latest

Research title

Immune regulation by cotrolling regulatory T cell-specific epigenome

Research overview

Aims
Analysis of immune cells in autoimmune diseases
Methods
single-cell RNA+VDJ-seq
Participants/materials
myasthenia gravis (MG) 2 cases, multiple sclerosis (MS) 4 cases, systemic lupus erythematosus (SLE) 3 cases, 3 healthy cases
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000704NGS (scRNA-seq, scVDJ-seq)
  • scRNA-seq + scVDJ-seq
Controlled-access (Type I)2023-11-20

Data provider

Principal investigator
Shimon Sakaguchi
Affiliation
Experimental Immunology, IFReC, Osaka University

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Specially Promoted Research
Study of the function and development of regulatory T cells
  • 16H06295
Leading Advanced Projects for medical innovation (LEAP), Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED)
Study of Immunoregulatory technology targeting regulatory T cells
  • JP18gm0010005

Related publications

No related publications.

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31