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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0243-v1Release info

Latest

Research title

Development of humanized mice for human immunity research/Construction of disease and treatment model using iPS cells derived from human hematopoitec cells.

Research overview

Aims
Evaluation of function of immue cells using humanized mice
Methods
RNA-seq or CAGE-seq
Participants/materials
RNAs extracted from cells derived from cord blood, and leukemia cells harvested from bone marrow aspirates or spleen cells of humanized mice generated from peripheral blood, bone marrow aspirates or samples from patients with Acute Myeloid Leukemia
URL

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000356NGS (RNA-seq, CAGE-seq)
  • RNA-seq
  • CAGE-seq
Controlled-access (Type I)2020-11-25

Data provider

Principal investigator
Fumihiko Ishikawa
Affiliation
Laboratory for Human Disease Models, Riken Center for Integrative Medical Sciences

Research projects

NameURL
Target AML project
N/A

Grants

No grants.

Related publications

TitleDOIDataset ID
Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive Acute Myeloid Leukemia
https://doi.org/10.1038/s43018-021-00177-w (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Jinyan HuangZhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, China. Biomedical big data center, the First Affiliated Hospital, Zhejiang UniversityChinaComprehensive analysis of alternative splicing in malignant tumors2022-03-15 – 2024-01-01
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31