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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0153-v1Release info

Latest

Research title

Multiomics analysis of rare cancers to identify genetic alterations related with pathogenesis and prognosis

Research overview

Aims
Identification of genetics alterations of dedifferentiated liposarcoma and tendon sheath giant cell tumors (TSGCT)
Methods
DNAs and RNAs were extracted from tumor and paired non-tumor tissues (peripheral blood or adjacent normal tissues). Whole exome sequencing (WES), RNA sequencing, and target capture sequencing were performed by HiSeq 2500 or MiSeq (Illumina).
Participants/materials
29 dedifferentiated liposarcoma and 36 TSGCT patients
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000257NGS (Exome, RNA-seq, Target Capture)
  • WES
  • RNA-seq
Controlled-access (Type I)2020-09-28
JGAD000258NGS (Exome, RNA-seq, Target Capture)
  • WES
  • RNA-seq
  • Targeted DNA sequencing
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Koichi Matsuda
Affiliation
Graduate School of Frontier Sciences, The University of Tokyo
Principal investigator
Makoto Hirata
Affiliation
Institute of Medical Science, The University of Tokyo

Research projects

NameURL
Japan Sarcome genome consortium
N/A

Grants

NameTitleProject number
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)
Genomic analysis of bone and soft tissue tumors and screening of their therapeutic targets and biomarkers
  • JP17cm0106520
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)
Genomic analysis of bone and soft tissue tumors and screening of their therapeutic targets and biomarkers
  • JP18cm0106535
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT), Japan Agency for Medical Research and Development (AMED)
Identification of novel therapeutic target of soft tissue tumors by genomic analysis.
  • JP15cm0106141
KAKENHI Grant-in-Aid for Scientific Research (A)
Analysis of fusion transcripts in bone and soft tissue tumors for indentification of novel disease biomarker and reorganization of disease classification.
  • 16H02676

Related publications

TitleDOIDataset ID
Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations
https://doi.org/10.1002/ijc.32421 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Valerie BruntonEdinburgh Cancer Research UK Centre, University of EdinburghUnited KingdomGenomic analysis of soft tissue sarcoma2021-07-09 – 2025-04-17
William TapperHuman development and health, University of SouthamptonUnited KingdomUtilising sarcoma omic information to identify disease gene networks and associated novel therapies for patients2022-11-14 – 2025-10-20
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31