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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0064-v1Release info

Latest

Research title

Construction of Geriatric Oncology Database for establishment of the Treatment Algorithm: Clinical Data and Questionnaire Survey Results in JapaneseElderly Cancer Patients Retrospective study

Research overview

Aims
To construct a Geriatric Oncology Database of genotype, methylation, gene expression, clinical data, and questionnaire survey results in Japanese elderly cancer patients and attempt to establish truly effective treatment strategy
Methods
1. Genome & Genetic research
Direct sequencing, TaqMan analysis, qRT-PCR, COBRA assay, cDNA microarray. Collection of clinical data and digitalization of them.
2. Retrospective study
Collection of clinical data and digitalization of them. Collection of questionnaires and digitalization of them.
Participants/materials
1. Genome & Genetic research
colorectal cancer: 106 cases, gastric cancer: 62 cases, lung cancer: 173 cases
2. Retrospective study
colorectal cancer: 313 cases, gastric cancer: 166 cases, lung cancer: 344 cases
diabetes and nephropathy: 300 cases, cardiovascular disorder: 357 cases, respiratory dysfunction: 49 cases
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD0000611. Genome & Genetic research
genotype, methylation, gene expression, clinical data for colorectal, gastric, or lung cancer patients.
2. Retrospective study
clinical data for colorectal cancer, gastric cancer, lung cancer, cardiovascular disorders, respiratory dysfunction, diabetes, or nephropathy patients.
  • Sanger sequencing + TaqMan + qRT-PCR + Microarray (薬剤代謝遺伝子 SNP / がん)
  • 臨床・治療情報
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Masahiko Nishiyama
Affiliation
Department of Molecular Pharmacology and Oncology, Gunma University Graduate School of Medicine

Research projects

NameURL
Third Term Comprehensive Control Research for Cancer Health and Labor Sciences Research Grants of the Ministry of Health, Labor and Welfare of Japan.
N/A

Grants

NameTitleProject number
Third Term Comprehensive Control Research for Cancer Health and Labor Sciences Research Grants of the Ministry of Health, Labor and Welfare of Japan.
Geriatric Oncology Database of genotypes and methylation, gene expression, clinical data, and survey results on psychosocial and physical conditions in Japanese elderly cancer patients to establish truly effective treatment strategy
  • 一般-010

Related publications

TitleDOIDataset ID
Impact of age on epidermal growth factor receptor mutation in lung cancer.
https://doi.org/10.1016/j.lungcan.2012.09.006 (opens in a new tab)
Association between a genome-wide association study-identified locus and the risk of lung cancer in Japanese population.
https://doi.org/10.1097/JTO.0b013e3182475028 (opens in a new tab)
Thoracic radiotherapy with or without daily low-dose carboplatin in elderly patients with non-small-cell lung cancer: a randomised, controlled, phase 3 trial by the Japan Clinical Oncology Group (JCOG0301)
https://doi.org/10.1016/S1470-2045(12)70139-0 (opens in a new tab)
Progression-free survival as a surrogate for overall survival in advanced/recurrent gastric cancer trials: a meta-analysis.
https://doi.org/10.1093/jnci/djt269 (opens in a new tab)
Risk factors associated with recurrence of surgically resected node-positive non-small cell lung cancer.
https://doi.org/10.1007/s00595-015-1301-5 (opens in a new tab)
Genetic and Prognostic Differences of Non-small Cell Lung Cancer between Elderly Patients and Younger Counterparts.
N/A

Controlled access users

No use of the controlled access data has been recorded.