Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0045-v1Release info

Latest

Research title

Transcriptome analysis of acute lymphoblastic leukemia in adolescents and young adults

Research overview

Aims: Screening of oncogenic fusion genes in acute lymphoblastic leukemia (ALL) in adolescents and young adults
Methods: RNA-seq by using HiSeq 2000 / 2500
Participants/materials: 99 Philadelphia chromosome-negative (Ph-) ALLs, 3 Philadelphia chromosome-positive (Ph+) ALLs, 5 cell lines, 8 normal hematopoietic cells
URL: https://www.ncc.go.jp/en/ri/division/genetics/index.html (opens in a new tab)

Datasets

Cart	Dataset ID	Type of data	Analysis method	Access criteria	Date published
	JGAD000047	NGS (RNA-seq)	RNA-seq	Controlled-access (Type I)	2020-09-28

Data provider

Principal investigator: Hiroyuki Mano
Affiliation: Division of Cellular Signaling, National Cancer Center Research Institute

Research projects

No research projects.

Grants

Name	Title	Project number
Leading Advanced Projects for medical innovation (LEAP), Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED)	Projects for exploration of therapeutic targets in cancer	15653406

Related publications

Title	DOI	Dataset ID
Recurrent DUX4 fusions in B-cell acute lymphoblastic leukemia of adolescents and young adults	https://doi.org/10.1038/ng.3535 (opens in a new tab)	JGAD000047

Controlled access users

Principal investigator	Affiliation	Country/Region	Research title	Period of data use	Dataset ID
Jinyan Huang	State Key Laboratory Of Medical Genomics, Rui-jin Hospital	China	Comparing analysis adult and Pediatric B-cell Acute Lymphoblastic Leukemia	2016-05-23 – 2017-03-27	JGAD000047
Robert Bradley	Public Health Sciences, Fred Hutchinson Cancer Research Center	Washington, United States	Repeat derepression and RNA-mediated toxicity in FSHD	2016-08-05 – 2027-04-09	JGAD000047
Christine Harrison	Northern Institute for Cancer Research, Newcastle University	United Kingdom	Re-analysis of Publically Available RNA-Seq Data from Patients with B-cell Precursor Acute Lymphoblastic Leukaemia	2019-05-07 – 2025-05-01	JGAD000047
Jinyan Huang	Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, China. Biomedical big data center, the First Affiliated Hospital, Zhejiang University	China	Comprehensive analysis of alternative splicing in malignant tumors	2022-03-15 – 2024-01-01	JGAD000047
Michiaki Hamada	Hamada Laboratory, Faculty of Science and Engineering, Waseda University	Japan	Construction of RNA-targeted Drug Discovery Database	2023-01-05 – 2027-10-31	JGAD000047