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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0045-v1Release info

Latest

Research title

Transcriptome analysis of acute lymphoblastic leukemia in adolescents and young adults

Research overview

Aims
Screening of oncogenic fusion genes in acute lymphoblastic leukemia (ALL) in adolescents and young adults
Methods
RNA-seq by using HiSeq 2000 / 2500
Participants/materials
99 Philadelphia chromosome-negative (Ph-) ALLs, 3 Philadelphia chromosome-positive (Ph+) ALLs, 5 cell lines, 8 normal hematopoietic cells
URL

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000047NGS (RNA-seq)
  • RNA-seq
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Hiroyuki Mano
Affiliation
Division of Cellular Signaling, National Cancer Center Research Institute

Research projects

No research projects.

Grants

NameTitleProject number
Leading Advanced Projects for medical innovation (LEAP), Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED)
Projects for exploration of therapeutic targets in cancer
  • 15653406

Related publications

TitleDOIDataset ID
Recurrent DUX4 fusions in B-cell acute lymphoblastic leukemia of adolescents and young adults
https://doi.org/10.1038/ng.3535 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Jinyan HuangState Key Laboratory Of Medical Genomics, Rui-jin HospitalChinaComparing analysis adult and Pediatric B-cell Acute Lymphoblastic Leukemia2016-05-23 – 2017-03-27
Robert BradleyPublic Health Sciences, Fred Hutchinson Cancer Research CenterWashington, United StatesRepeat derepression and RNA-mediated toxicity in FSHD2016-08-05 – 2027-04-09
Christine HarrisonNorthern Institute for Cancer Research, Newcastle UniversityUnited KingdomRe-analysis of Publically Available RNA-Seq Data from Patients with B-cell Precursor Acute Lymphoblastic Leukaemia2019-05-07 – 2025-05-01
Jinyan HuangZhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, China. Biomedical big data center, the First Affiliated Hospital, Zhejiang UniversityChinaComprehensive analysis of alternative splicing in malignant tumors2022-03-15 – 2024-01-01
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31