Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0027-v1Release info

Latest

Research title

Identification of genetic polymorphism on aggressive periodontitis

Research overview

Aims: To identify polymorphisms (SNP and Indel) of responsible genes for Japanese aggressive periodontitis by whole exon sequencing (WES) analysis. Then, functional analyses forf the responsible genes were assessed by in vivo/vitro biological experiments.
Methods: WES by using of HiSeq 2000 (Illumina).
Participants/materials: 44 Japanese aggressive periodontitis patients
URL: N/A

Datasets

Cart	Dataset ID	Type of data	Analysis method	Access criteria	Date published
	JGAD000024	NGS (Exome)	WES	Controlled-access (Type I)	2020-09-28
	JGAD000040	NGS (Exome)	WES	Controlled-access (Type I)	2020-09-28

Data provider

Principal investigator: Shinya Murakami
Affiliation: Division of Oral Biology and Disease Control, Department of Periodontology, Osaka University Graduate School of Dentistry

Research projects

No research projects.

Grants

Name	Title	Project number
KAKENHI Grant-in-Aid for Scientific Research (A)	Identification of genetic risk factors on aggressive periodontitis in a Japanese population	15H02579
KAKENHI Grant-in-Aid for Scientific Research (C)	Effects of cathepsin A on the regeneration of periodontal tissue	15K11385

Related publications

No related publications.

Controlled access users

No use of the controlled access data has been recorded.