hum0043 Data Summary
#Data dictionaries and QC manuals
| Dataset ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| File_list_J-ADNI.pdf | List of Downloadable Files | Unrestricted-access | 2016/1/29 |
| Data_dictionary_J-ADNI.tsv | Data Dictionary（Description of each field in table data） | Unrestricted-access | 2016/1/29 |
| J-ADNI_MRIQC_Ver1.1.pdf | Quality Control Procedures for MRI | Unrestricted-access | 2016/1/29 |
| J-ADNI_PETQC_Ver1.1.pdf | Quality Control Procedures for PET | Unrestricted-access | 2016/1/29 |
- There is a special mention on a small portion of participants. Please make sure of it before use. Records of the participants are marked for attention in the "s.m." column of table data.
- When the research results including the data which were downloaded from NHA/DRA, are published or presented somewhere, the data user must refer the papers which are related to the data, or include in the acknowledgment. Learn more.
- Citation on publication for scientific papers using J-ADNI data.
#1．Clinical and Psychometric Tests
| CRF Name | CRF Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|---|
| ADAS*1 | ADAS-Cognitive Behavior | ADAS_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| ADASSCORES | ADAS Sub-Scores and Total Scores | ADASSCORES_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| ADSXLIST | Diagnosis and Symptoms Checklist | ADSXLIST_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| ARM | Diagnosis/Scan Category Assignment | ARM_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| BLCHANGE | Diagnostic Summary - Baseline Changes | BLCHANGE_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| BLSCHECK | Baseline Symptoms Checklist | BLSCHECK_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| CDR*2 | Clinical Dementia Rating | CDR_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| CONVERSIONS | Conversions Confirmed by Conversion Committee | CONVERSIONS_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| EXCLUSIO | Exclusion Criteria | EXCLUSIO_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| FAQ*3 | Functional Assessment Questionnaire | FAQ_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| FHQ | Family History Questionnaire | FHQ_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| GDSCALE*4 | Geriatric Depression Scale | GDSCALE_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| INCLUSIO | Inclusion Criteria | INCLUSIO_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| MEDHIST | Medical History | MEDHIST_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| MMSE*5 | Mini Mental State Exam | MMSE_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| MODHACH*6 | Modified Hachinski | MODHACH_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| NEUROBAT | Neuropsychological Battery | NeuroBAT_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| NEUROEXM | Neurological Exam | NEUROEXM_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| NPIQ*7 | Neuropsychiatric Inventory Q | NPIQ_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| PDXCONV | Diagnostic Summary | PDXCONV_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| PHYSICAL | Physical Exam | PHYSICAL_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| PTDEMOG | Participant Demographic Information | PTDEMOG_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| RECFHQ | Family History Questionnaire Subtable | RECFHQ_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| REGISTRY | Registry | REGISTRY_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| TREATDIS | Early Discontinuation and Withdrawal | TREATDIS_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
| VITALS | Vital Signs | VITALS_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_cognitive.zip |
※1：Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. The American Journal of Psychiatry. 1984;141(11):1356–1364. PMID 6496779
※2：Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982 Jun;140:566-72. PMID 7104545
※3：Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol. 1982;37:323–329. PMID 7069156
※4：Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982-83;17(1):37-49. PMID 7183759
※5：Folstein, MF; Folstein, SE; McHugh, PR (1975). ""Mini-mental state". A practical method for grading the cognitive state of patients for the clinician". Journal of Psychiatric Research 12 (3): 189–98. PMID 1202204
※6：Hachinski VC. Multi-infarct dementia: a cause of mental deterioration in the elderly. Lancet. 1974;2:207–9. PMID 4135618
※7：Cummings, J., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A., & Gornbein, J. (1994). The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia. Neurology, 44, 2308-2314. PMID 7991117
#2．Special Mention
| Contents | File Name | File Format（Extension） |
|---|---|---|
| Multidomain Amnestic MCI | SpecialMention.xlsx | Microsoft Excel (.xlsx) |
| Exceptional Enrollement | SpecialMention.xlsx | Microsoft Excel (.xlsx) |
| Delayed Interval for LMII | SpecialMention.xlsx | Microsoft Excel (.xlsx) |
| Exceptional Use of Prohibited Drugs | SpecialMention.xlsx | Microsoft Excel (.xlsx) |
| Cases Converted Twice | SpecialMention.xlsx | Microsoft Excel (.xlsx) |
| Additional Comments on Consent | SpecialMention.xlsx | Microsoft Excel (.xlsx) |
#3．Biochemical Tests
| CRF Name | CRF Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|---|
| APOE | ApoE Genotyping | APOE_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_biochemical.zip |
| BLOOD | Perpheral Blood | BLOOD_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_biochemical.zip |
| BLOOD_EXAMITEM | Explanation and Normal Values of Examination Item in BLOOD | BLOOD_EXAMITEM_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_biochemical.zip |
| CSF | Cerebrospinal Fluid (CSF) | CSF_J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_biochemical.zip |
#4．MRI scan (1.5T, 3T)
#4.1 Quality Control
| CRF Name | CRF Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|---|
| MRIQC | MRI Scan Information | MRIQC-J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_mriqc.zip |
※ See J-ADNI_MRIQC_Ver1.1.pdf and MRI Scanner list for MRI quality control procedures
#4.2 MRI Images
FreeSurfer version 5.1 was used for analysis.
| Directory Name | Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|---|
| Original | Raw MRI Images obtained from MRI Scanners | See File_list_J-ADNI.pdf | Neuroimaging Informatics Technology Initiative (NIfTI) image file format (.nii) | JADNI####_mri.zip |
| DistortionCorrected | Distortion in the raw MRI Image was corrected by using methods developed in J-ADNI project | See File_list_J-ADNI.pdf | Neuroimaging Informatics Technology Initiative (NIfTI) image file format (.nii) | JADNI####_mri.zip |
#4.3 FreeSurfer Analysis
| Analysis Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|
| Subcortical Segmentation containing the Volumes of Specific Structures | aseg.stats | Tab Separated Variables | JADNI_freesurfer.zip |
| Cortical Parcellation containing Thickness of Specific Structures based on Destrieux Atlas | lh.aparc.a2009s.stats（Left Hemisphere） rh.aparc.a2009s.stats（Right Hemisphere） | Tab Separated Variables | JADNI_freesurfer.zip |
| Cortical Parcellation containing Thickness of Specific Structures based on Desikan-Killiany Atlas | lh.aparc.stats（Left Hemisphere） rh.aparc.stats（Right Hemisphere） | Tab Separated Variables | JADNI_freesurfer.zip |
| Cortical Parcellation containing Thickness of Specific Structures based on Broadman Area Map | llh.BA.stats（Left Hemisphere） rh.BA.stats（Right Hemisphere） | Tab Separated Variables | JADNI_freesurfer.zip |
| Cortical Parcellation containing Curvature for Cortical Thickness | lh.curv.stats（Left Hemisphere） rh.curv.stats（Right Hemisphere） | Tab Separated Variables | JADNI_freesurfer.zip |
| Cortical Parcellation containing Thickness of Entorhinal Cortex | lh.entorhinal_exvivo.stats（Left Hemisphere） rh.entorhinal_exvivo.stats（Right Hemisphere） | Tab Separated Variables | JADNI_freesurfer.zip |
| Subcortical Segmentation containing White Matter Parcellation Volumes | wmparc.stats | Tab Separated Variables | JADNI_freesurfer.zip |
#5. PET Scan (FDG and Amyloid (PIB, BF227))
The FDG PET images were pre-processed with step 3, "CO-REG, AVG, STANDARDIZED IMAGE AND VOXEL SIZE" of the ADNI protocol.
See https://adni.loni.usc.edu/data-samples/adni-data/neuroimaging/pet/ for details.
#5.1 Quality Control
| CRF Name | CRF Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|---|
| PETQC | PET Scan Information | PETQC-J-ADNI.tsv | Tab Separated Variables (.tsv) | JADNI_petpc.zip |
※ See J-ADNI_PETQC_Ver1.1.pdf and PET Scanner list for PET quality control procedures.
#5.2 PET Images
| Description | File Name | File Format（Extension） | ZIP File Name |
|---|---|---|---|
| PET Images（Post-processed） | See File_list_J-ADNI.pdf | Analyze image file format (.hdr/.img) | JADNI####_pet.zip |
#MRI scanner list
| MRI SCANNER_VENDOR | MRI SCANNER_MODEL |
|---|---|
| GE | SIGNA EXCITE |
| GE | Discovery MR750 |
| GE | GENESIS_SIGNA |
| GE | SIGNA HDxt |
| Hitachi | ECHELON |
| Philips | Achieva |
| Philips | Ingenia |
| Philips | Intera |
| Siemens | Avanto |
| Siemens | MAGNETOM VISION |
| Siemens | Sonata |
| Siemens | Symphony |
| Siemens | TrioTim |
| Toshiba | EXCELART Vantage powered by Atlas |
| Toshiba | EXCELART Vantage ZGV |
#PET scanner list
| PET SCANNER_VENDOR | PETSCANNER_MODEL |
|---|---|
| GE | Advance |
| GE | Discovery ST Elite |
| GE | Discovery ST Elite Performance |
| Philips | GEMINI GXL |
| Shimadzu | Eminence G/X |
| Shimadzu | Eminence SOPHIA B/L |
| Shimadzu | Eminence SOPHIA G/M |
| Shimadzu | Eminence SOPHIA G/X |
| Shimadzu | HEADTOME V |
| Siemens | Biograph 16 |
| Siemens | Biograph 6 |
| Siemens | Biograph TrueV |
| Siemens | ECAT ACCEL |
| Siemens | ECAT EXACT HR+ |
| Siemens | ECAT EXACT HR47 |
| Toshiba | Aquiduo |