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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD000994

Type of data
NGS (WGS, snRNA-seq, snATAC-seq)
Access criteria
Controlled-access (Type I)
Total data volume
1.8 TB
File formats
  • FASTQ
Research
hum0488
Date published
2026-01-06
Date modified
2026-01-06
DDBJ Search
JGAD000994 (opens in a new tab)
JGA Study
JGAS000852 (opens in a new tab)

Analysis method

WGS

Materials and participants
ALS (ICD10: G12.2): 6 cases
non-ALS: 6 cases
frozen brain (motor cortex) and spinal cord (lumber spinal cord L4 and L5) tissues
  • Health status
    Mixed
  • Subject count
    12 (Individual)
Disease
ALS (G122)
Sample description
DNAs extracted from frozen samples
  • Tissue
    Brain, Spinal cord
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
WGS
Target
N/A
Reagent kit
TruSeq DNA PCR-Free Library Prep Kit
Fragmentation
included in the above library construction kit
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp
Data use policy
NBDC data sharing policy (JGAP000001)

snRNA-seq

Materials and participants
ALS (ICD10: G12.2): 6 cases
non-ALS: 6 cases
frozen brain (motor cortex) and spinal cord (lumber spinal cord L4 and L5) tissues
  • Health status
    Mixed
  • Subject count
    12 (Individual)
Disease
ALS (G122)
Sample description
RNAs extracted from nuclei obtained from frozen samples
  • Tissue
    Brain, Spinal cord
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
scRNA-seq
Target
N/A
Reagent kit
Chromium Next GEM Single Cell 3' v3.1
Fragmentation
manufacturer's protocol
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp
Data use policy
NBDC data sharing policy (JGAP000001)

snATAC-seq

Materials and participants
ALS (ICD10: G12.2): 4 cases
non-ALS: 4 cases
frozen brain (motor cortex) and spinal cord (lumber spinal cord L4 and L5) tissues
  • Health status
    Mixed
  • Subject count
    8 (Individual)
Disease
ALS (G122)
Sample description
DNAs extracted from nuclei obtained from frozen samples
  • Tissue
    Brain, Spinal cord
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
scATAC-seq
Target
N/A
Reagent kit
Chromium Next GEM Single Cell Multiome ATAC + Gene Expression
Fragmentation
manufacturer's protocol
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp
Data use policy
NBDC data sharing policy (JGAP000001)