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Dataset ID

JGAD000840

Type of data
NGS (Exome, RNA-seq)
Access criteria
Controlled-access (Type I)
Total data volume
927 GB
File formats
  • FASTQ
  • BAM
Research
hum0317
Date published
2024-06-11
Date modified
2024-06-11

Analysis method

WES

Materials and participants
Non-small cell lung cancer (ICD10: C349)
- germline tissues: 3 cases, 3 samples
- tumor tissues: 4 cases, 4 samples
- tumor tissues from PDX: 4 cases, 12 samples
Cancer (ICD10: C00-C97)
- germline tissues: 44 + 269 cases, 44 + 269 samples
- tumor tissues: 125 cases 125 samples
- tumor tissues from PDX: 52 + 269 cases, 52 + 795 samples
Cancer (52 cases)
  • Health status
    Affected
  • Subject count
    770 (Individual)
Disease
Non-small cell lung cancer (C349)
Cancer
Sample description
DNAs extracted from germline tissues, tumor tissues, and tumor tissues from PDX
  • Tissue
    PDX
  • Tumor / normal
    Mixed
Sample provider
N/A
Experimental method
WES
Target
N/A
Reagent kit
Twist Comprehensive Exome Panel
Fragmentation
Enzymatic fragmentation, Ultrasonic fragmentation
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp
Reference genome
GRCh38
GRCm38

RNA-seq

Materials and participants
Non-small cell lung cancer (ICD10: C349)
- tumor tissues: 2 cases, 2 samples,
- tumor tissues from PDX: 4 cases, 12 samples
Cancer (ICD10: C00-C97)
- tumor tissues from PDX: 51 cases, 51 samples
  • Health status
    Affected
  • Subject count
    57 (Individual)
Disease
Non-small cell lung cancer (C349)
Cancer
Sample description
RNAs extracted from tumor tissues and tumor tissues from PDX
  • Tissue
    PDX
  • Tumor / normal
    Tumor
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Reagent kit
NEBNext Ultra Directional RNA Library Prep Kit for Illumina
Fragmentation
Heat treatment
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp