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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD000122

Type of data
NGS (Exome, RNA-seq, RNA access),
Methylation array, SNP array
Access criteria
Controlled-access (Type I)
Total data volume
6.6 TB
File formats
  • FASTQ
  • BAM
  • TSV
Research
hum0094
Date published
2020-09-28
Date modified
2026-09-26
DDBJ Search
JGAD000122 (opens in a new tab)
JGA Study
JGAS000113 (opens in a new tab)

Analysis method

WES

Materials and participants
MSI-H CRC (ICD10: C18, 19, 20): 149 cases
  • Health status
    Affected
  • Subject count
    149 (Individual)
Disease
MSI-H CRC (C18, C19, C20)
Sample description
DNAs extracted from tumor tissues and paired non-tumor tissues or peripheral blood cells as non-tumor tissues
  • Tissue
    Peripheral blood
  • Tumor / normal
    Mixed
Sample provider
N/A
Experimental method
WES
Target
N/A
Reagent kit
NEBNext Ultra DNA Library Prep Kit for Illumina
SureSelect Human All Exon V5
SureSelect Human All Exon V6
Fragmentation
Ultrasonic fragmentation (Covaris)
Platform
Illumina HiSeq 2000
Illumina HiSeq 2500
Illumina NovaSeq 6000
Read type
Paired-end
Read length
MSI-H colorectal cancer: 104 bp
135 bp
Reference genome
GRCh37
GRCh38
Data use policy
NBDC data sharing policy (JGAP000001)
No use by private-sector companies (JGAP000003)

RNA-seq

Materials and participants
MSI-H CRC (ICD10: C18, 19, 20): 94 cases
  • Health status
    Affected
  • Subject count
    94 (Individual)
Disease
MSI-H CRC (C18, C19, C20)
Sample description
RNAs extracted from tumor tissues
  • Tissue
    Breast, Colon, Lung, Salivary gland, Soft tissue
  • Tumor / normal
    Tumor
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Reagent kit
NEBNext Ultra Directional RNA Library Prep Kit for Illumina
TruSeq RNA Exome
Fragmentation
Heat treatment
Platform
Illumina HiSeq 2000
Illumina HiSeq 2500
Read type
Paired-end
Read length
MSI-H colorectal cancer: 104 bp
135 bp
Data use policy
NBDC data sharing policy (JGAP000001)
No use by private-sector companies (JGAP000003)

RNA access

Materials and participants
MSI-H CRC (ICD10: C18, 19, 20): 18 cases
  • Health status
    Affected
  • Subject count
    18 (Individual)
Disease
MSI-H CRC (C18, C19, C20)
Sample description
RNAs extracted from tumor tissues
  • Tumor / normal
    Tumor
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Reagent kit
TruSeq RNA Exome
Fragmentation
Heat treatment
Platform
Illumina HiSeq 2000
Illumina HiSeq 2500
Read type
Paired-end
Read length
104 bp
135 bp
Phenotype data
Included
Data use policy
NBDC data sharing policy (JGAP000001)

Genotyping by array (CNV)

Materials and participants
MSI-H CRC (ICD10: C18, 19, 20): 25 cases
  • Health status
    Mixed
  • Subject count
    25 (Individual)
Disease
MSI-H CRC (C18, C19, C20)
Sample description
DNAs extracted from tumor tissues and paired non-tumor tissues
  • Tumor / normal
    Mixed
Sample provider
N/A
Experimental method
Genotyping by array
Target
N/A
Reagent kit
HumanOmni2.5 BeadChip Kit
Platform
Illumina HumanOmni2.5
QC and filtering
As described in 'Illumine Infinium Assay Ver.2.1.'
Analysis method
GenomeStudio (Illumina)
Variant count
N/A
Data use policy
NBDC data sharing policy (JGAP000001)

メチル化アレイ

Materials and participants
MSI-H CRC (ICD10: C18, 19, 20): 93 cases
normal tissues: 20 samples
  • Health status
    Affected
  • Subject count
    93 (Individual)
Disease
MSI-H CRC (C18, C19, C20)
Sample description
DNAs extracted from tumor tissues and paired non-tumor tissues
  • Tumor / normal
    Mixed
Sample provider
N/A
Experimental method
Methylation array
Target
N/A
Reagent kit
Infinium MethylationEPIC BeadChip Kit
Platform
Illumina Infinium MethylationEPIC
QC and filtering
Detection P-value >= 0.05
Normalization
N/A
Analysis method
GenomeStudio (Illumina)
Probe count
867,926 probes (Count)
Phenotype data
Included
Data use policy
NBDC data sharing policy (JGAP000001)