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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0535-v1Release info

Latest

Research title

A study on the impact of skin diseases on cellular alterations in skin component cells, blood, and other organ cells

Research overview

Aims
To perform comprehensive genomic and transcriptomic analyses of DNA and RNA obtained from the skin, blood, and related organs of patients with dermatological diseases, in order to elucidate disease mechanisms and provide a basis for developing novel therapeutic strategies.
Methods
ATAC-seq
Participants/materials
Epidermal keratinocytes from psoriatic lesions, clinically healed skin of the same patients, and healthy control skin
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000986NGS (ATAC-seq)
  • ATAC-seq
Controlled-access (Type I)2025-10-20

Data provider

Principal investigator
Sayaka Shibata
Affiliation
Department of Dermatology, Graduate School of Medicine, The University of Tokyo

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (C)
Mechanisms for Chronic Inflammation of Skin Diseases Due to Resilience Failure and Treatment Strategies
  • 24K11447
Precursory Research for Innovative Medical care (PRIME), Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED)
Mechanistic Elucidation of Stress Memory-Driven Chronic Inflammation and Visualization of Stress Sensing
  • JP24gm6910016
Lydia O'Leary Memorial Pias Dermatological Foundation
Elucidation of the Regulatory Mechanisms of Psoriatic Pathogenesis Mediated by DNA Environment and Super-Enhancers
N/A

Related publications

No related publications.

Controlled access users

No use of the controlled access data has been recorded.