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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0359-v1Release info

Latest

Research title

Genomic and Epigenetic Analysis on T/NK-cell lymphoma

Research overview

Aims
The pathogenesis of T/NK cell lymphoma is heterogeneous and complex, and optimal treatment has not been established, partly because the disease is relatively rare. Comprehensive analysis of genomic, epigenomic, and gene expression abnormalities occurring in T/NK cell lymphomas may not only clarify the pathogenesis of the disease, but also identify distinctive disease units, new molecular targets, and prognostic factors. In this study, we will comprehensively analyze the genome, epigenome, and gene expression of T/NK cell lymphoma, and clarify the molecular pathogenesis of the disease by examining the relationship with histopathology, disease type, and prognosis.
Methods
Targeted DNA sequencing of tumor (lymphoma) tissues
Participants/materials
Extranodal NK/T-cell lymphoma, nasal type
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000668NGS (Target Capture)
  • Targeted DNA sequencing
Controlled-access (Type I)2022-08-07

Data provider

Principal investigator
Naoki Oishi
Affiliation
Department of Pathology, University of Yamanashi

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (C)
Histopathologic Features Associated with Molecular Subtypes of Extranodal NK/T Cell Lymphoma
  • 21K06883
Kurozumi Medical Foundation
Development of Molecular-based Pathologic Prognostic Stratification for Extranodal NK/T cell lymphoma, Nasal Type
N/A

Related publications

TitleDOIDataset ID
Genetic and immunohistochemical profiling of NK/T-cell Lymphomas reveals prognostically relevant BCOR-MYC association

Controlled access users

No use of the controlled access data has been recorded.