Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0348-v1Release info

Latest

Research title

Analysis of ATL progression by CD30 signaling and its biomarkers

Research overview

Aims: To elucidate the mechanism of the tumorigenic process involving genomic aberrations by CD30 signaling in HTLV-1-infected T-cells
Methods: CD30+ATL cells, CD30-ATL cells, and HTLV-1 uninfected lymphocytes were sorted by FACS AriaIII. DNA was extracted from each sorted cell and used for whole exome sequencing analysis and array-CGH analysis.
Participants/materials: Adult T-cell leukemia/lymphoma (ATL): 8 cases
URL: N/A

Datasets

Cart	Dataset ID	Type of data	Analysis method	Access criteria	Date published
	JGAD000656	NGS (Exome) array-CGH	WES アレイ CGH	Controlled-access (Type I)	2023-05-16

Data provider

Principal investigator: Makoto Nakashima
Affiliation: Graduate School of Frontier Sciences, The University of Tokyo

Research projects

No research projects.

Grants

Name	Title	Project number
KAKENHI Grant-in-Aid for Early-Career Scientists	Analysis of ATL progression by CD30 signaling and its biomarkers	19K16580
KAKENHI Grant-in-Aid for Early-Career Scientists	The oncogenic driving force of CD30 signaling-induced chromosomal instability in adult T-cell leukemia/lymphoma	22K15420

Related publications

Title	DOI	Dataset ID
The oncogenic driving force of CD30 signaling-induced chromosomal instability in adult T-cell leukemia/lymphoma	https://doi.org/10.1111/cas.15706 (opens in a new tab)	JGAD000656

Controlled access users

No use of the controlled access data has been recorded.