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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0316-v1Release info

Latest

Research title

Whole-genome sequencing of esophageal cancer to elucidate pathogenesis and search for treatment-sensitive markers

Research overview

Aims
Search for genomic mutations in esophageal squamous cell carcinoma in Japanese.
Methods
NGS libraries using DNA extracted from non-tumor tissues (normal tissues) and tumor tissues and NGS libraries using RNA extracted from tumor tissues in resected sections of esophageal squamous cell carcinoma are prepared and sequenced using Illumina HiSeq 2000/2500.
Participants/materials
tumor tissues and non-tumor tissues of esophageal squamous cell carcinoma cases
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000654NGS (WGS)
NGS (RNA-seq)
  • WGS
  • RNA-seq
Controlled-access (Type I)2022-05-25

Data provider

Principal investigator
Hidewaki Nakagawa
Affiliation
RIKEN Center for Integrative Medical Sciences Laboratory of Genome Sequencing Analysis

Research projects

No research projects.

Grants

NameTitleProject number
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)
Search for seeds for the development of novel immunotherapies and combined immunotherapies by cancer genome analysis
  • JP20cm0106552

Related publications

TitleDOIDataset ID
Immuno-genomic Profiling of Biopsy Specimens Predicts Neoadjuvant Chemotherapy Response in Esophageal Squamous Cell Carcinoma
https://doi.org/10.1016/j.xcrm.2022.100705 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31
Shizuki SugitaDivision of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of MedicineJapanElucidation of the impact of neoadjuvant therapy on tumor microenvironment and the factor of early recurrence in esophageal cancer patients by whole genome sequencing2023-04-07 – 2023-12-07