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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0275-v1Release info

Latest

Research title

Comprehensive analysis of genetic abnormalities in solid tumors

Research overview

Aims
Through an integrated genetic study involving whole exome sequencing analysis, we delineate the landscape of genetic alterations in solid tumors.
Methods
We collected additional biopsied gastric tissues from nine subjects who underwent diagnostic endoscopy and biopsy for upper gastrointestinal symptoms. Genomic DNA isolated from each gland was subjected to whole exome sequencing.
Participants/materials
Nine subjects without Helicobacter pylori (Hp) infection or gastric cancer were included as the healthy population. Two biopsies of normal gastric mucosa were obtained from each subject.
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000424NGS (Exome)
  • WES
Controlled-access (Type I)2021-07-19

Data provider

Principal investigator
Seishi Ogawa
Affiliation
Kyoto University Graduate School of Medicine

Research projects

NameURL
Comprehensive analysis of genetic abnormalities in solid tumors / Department of Pathology and Tumor Biology
N/A

Grants

NameTitleProject number
Core Research and Evolutional Science and Technology, Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-CREST)
Tissue remodeling and functional deterioration associated with aging and inflammation
  • JP20gm1110011

Related publications

TitleDOIDataset ID
Indolent feature of Helicobacter pylori-uninfected intramucosal signet ring cell carcinomas with CDH1 mutations
https://doi.org/10.1007/s10120-021-01191-8 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.