Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0247-v1Release info

Latest

Research title

Research for gene mutations in cancer representing immune status of the patients

Research overview

Aims: Establishment of a tumor infiltrating lymphocytes (TIL) therapy for malignant melanoma
Methods: Exome sequencing of melanoma tissues for TIL production and paired peripheral blood mononuclear cells (PBMC)
Participants/materials: human melanoma and paired PBMC
URL: N/A

Datasets

Cart	Dataset ID	Type of data	Analysis method	Access criteria	Date published
	JGAD000349	NGS (Exome)	WES	Controlled-access (Type I)	2021-01-05
	DRA010773	NGS (Exome)	WES	Unrestricted-access	2021-01-05

Data provider

Principal investigator: Takashi Iwata
Affiliation: Department of Obsterics and Gynecology, Keio University School of Medicine

Research projects

No research projects.

Grants

Name	Title	Project number
Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)	Pilot study of adoptive cell therapy using cultured tumor infiltrating lymphocytes with lympho-depleting non-myeloablative preconditioning for patients with metastatic melanoma	JP17ck0106158

Related publications

Title	DOI	Dataset ID
Pilot study of adoptive cell therapy using cultured tumor infiltrating lymphocytes for Japanese melanoma patients refractory to immune-checkpoint inhibitors	https://doi.org/10.1111/cas.15009 (opens in a new tab)	JGAD000349 DRA010773

Controlled access users

Principal investigator	Affiliation	Country/Region	Research title	Period of data use	Dataset ID
Takuya Yamamoto	Center for Intractable Diseases and ImmunoGenomics, National Institutes of Biomedical Innovation, Health and Nutrition	Japan	Basic research for vaccine development against gastrointestinal cancer and malignant melanoma based on the identification of novel cancer antigens	2024-11-12 – 2026-03-31	JGAD000349