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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0229-v1Release info

Latest

Research title

Identification and characterization of molecular markers in aging and neuronal disorders

Research overview

Aims
Identification of age associated molecular markers from blood cells using a single-cell RNA-seq technology
Methods
Single-cell RNA-seq using 10X Genomics library kit
Participants/materials
Supercentenarian (over 110 years old), family members, and unrelated donors
URL

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000324NGS (scRNA-seq)
  • scRNA-seq
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Piero Carninci
Affiliation
RIKEN Center for Integrative Medical Sciences

Research projects

No research projects.

Grants

No grants.

Related publications

TitleDOIDataset ID
Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.
https://doi.org/10.1073/pnas.1907883116 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Bo LiLyda Hill Department of Bioinformatics, UT Southwestern Medical CenterTexas, United StatesUsing peripheral T cell repertoire as an immune reporter to detect early-stage ovarian cancer2020-08-17 – 2022-05-24
elizabeth gaskellBroad InstituteUnited StatesInvestigating transcriptomic and epigenomic alterations over human aging2022-11-15 – 2026-08-12
Mohammad Mahdi KarimiComprehensive Cancer Centre, King's College LondonUnited KingdomFunctional role of transposable elements in ageing2023-07-18 – 2025-06-06
feng liBiotherapy Center, The First Affiliated Hospital of Zhengzhou UniversityChinaStudy to Improve Persistence and Antitumor Activity of CAR-T Cells2026-09-25 – 2027-01-31