Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0226-v1Release info

Latest

Research title

Genomic and genetic analysis of upper gastrointestinal tumors and elucidation of its clinicopathological significance.

Research overview

Aims: Identification of lifestyle and germline mutations (genetic factors) that predispose to gastric cancer in an Asian population
Methods: Whole exome sequencing (NGS) and whole transcriptome seuquencing (NGS) analyses
Participants/materials: Stomach adenocarcinoma patients
URL: N/A

Datasets

Cart	Dataset ID	Type of data	Analysis method	Access criteria	Date published
	JGAD000322	NGS (Exome, RNA-seq)	WES	Controlled-access (Type I)	2021-12-02
	JGAD000323	NGS (Exome, RNA-seq)	RNA-seq	Controlled-access (Type I)	2021-12-02

Data provider

Principal investigator: Hiroyuki Aburatani
Affiliation: RCAST, the University of Tokyo

Research projects

Name	URL
Genome Science laboratory	https://www.genome.rcast.u-tokyo.ac.jp/en/research (opens in a new tab)

Grants

Name	Title	Project number
KAKENHI Grant-in-Aid for Scientific Research (S)	Elucidation of the evolution of cancer cell populations by integrative genomic analysis	24221011
KAKENHI Grant-in-Aid for Scientific Research (A)	Comprehensive understanding of interdependent signaling between cancer and the stroma	16H02481
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)	Identification of the mechanism of development and progression of human epithelial tumors and the novel therapeutic targets	JP19cm0106502
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)	Elucidation of the diversity of gastric cancer genomics with a focus on humoral immunity and the exploration of intervention methods.	JP19cm0106551
Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)	Integrated analysis of large-scale Japanese cancer genomic, omics, and clinical data for international collaborative research and construction of a knowledge base for the promotion of genomic medicine	JP20ck0106547

Related publications

Title	DOI	Dataset ID
Defined lifestyle and germline factors predispose Asian populations to gastric cancer	https://doi.org/10.1126/sciadv.aav9778 (opens in a new tab)	JGAD000322 JGAD000323 JGAD000320 (hum0227) JGAD000321 (hum0227)

Controlled access users

Principal investigator	Affiliation	Country/Region	Research title	Period of data use	Dataset ID
Michiaki Hamada	Hamada Laboratory, Faculty of Science and Engineering, Waseda University	Japan	Construction of RNA-targeted Drug Discovery Database	2023-01-05 – 2027-10-31	JGAD000323
Tetsuo Ushiku	Department of Pathology, Graduate School of Medicine, The University of Tokyo	Japan	Genetic analysis of upper gastrointestinal tumors and their clinicopathological significance	2023-03-24 – 2028-03-31	JGAD000322 JGAD000323