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NBDC Research ID:hum0226-v1
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Title

Genomic and genetic analysis of upper gastrointestinal tumors and elucidation of its clinicopathological significance.

Research overview

Aims: Identification of lifestyle and germline mutations (genetic factors) that predispose to gastric cancer in an Asian population

Methods: Whole exome sequencing (NGS) and whole transcriptome seuquencing (NGS) analyses

Targets: Stomach adenocarcinoma patients

Datasets

Dataset ID
Access type
Type of data
Release date
JGAD000322Controlled-access (Type I)NGS (Exome, RNA-seq)2021-12-02
JGAD000323Controlled-access (Type I)NGS (Exome, RNA-seq)2021-12-02

Data provider

    Principal Investigator
    Hiroyuki Aburatani
    Affiliation
    RCAST, the University of Tokyo

Research projects

Name
URL
Genome Science laboratoryhttps://www.genome.rcast.u-tokyo.ac.jp/en/research

Grants

Name
Title
Project number
KAKENHI Grant-in-Aid for Scientific Research (S)Elucidation of the evolution of cancer cell populations by integrative genomic analysis
  • 24221011
KAKENHI Grant-in-Aid for Scientific Research (A)Comprehensive understanding of interdependent signaling between cancer and the stroma
  • 16H02481
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)Identification of the mechanism of development and progression of human epithelial tumors and the novel therapeutic targets
  • JP19cm0106502
Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)Elucidation of the diversity of gastric cancer genomics with a focus on humoral immunity and the exploration of intervention methods.
  • JP19cm0106551
Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)Integrated analysis of large-scale Japanese cancer genomic, omics, and clinical data for international collaborative research and construction of a knowledge base for the promotion of genomic medicine
  • JP20ck0106547

Related publications

Title
DOI
Datasets
Defined lifestyle and germline factors predispose Asian populations to gastric cancerhttps://doi.org/10.1126/sciadv.aav9778

Controlled access users

Principal Investigator
Affiliation
Country/Region
Research title
Period of data use
Data in use (Dataset ID)
Hamada MichiakiWaseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-052027-10-31
Ushiku TetsuoThe University of TokyoJapanGenetic analysis of upper gastrointestinal tumors and their clinicopathological significance2023-03-242028-03-31