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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0158-v3Release info

Latest

Research title

Genome sequencing analysis for liver cancer

Research overview

Aims
To investigate genomic alterations of Japanese liver cancers
Methods
DNAs and RNAs were extracted from liver cancer tissues and paired non-cancer (normal) tissues or blood samples. NGS libaraies were prepared for whole genome sequencing (WGS) and RNA-seq. Sequencing was perfomred by Illumina HiSeq or Genome Analyzer.
Participants/materials
DNAs and RNAs extracted from cancer tissues and normal tissues of Japanese liver cancer patients.
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000228NGS (WGS)
NGS (RNA-seq)
  • WGS
Controlled-access (Type I)2020-09-28
JGAD000404bam/gvcf data of NGS (WGS)
  • WGS
Controlled-access (Type I)2021-05-25
JGAD000229NGS (WGS)
NGS (RNA-seq)
  • RNA-seq
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Hidewaki Nakagawa
Affiliation
RIKEN Center for Integrative Medical Sciences

Research projects

No research projects.

Grants

No grants.

Related publications

TitleDOIDataset ID
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
https://doi.org/10.1038/ng.3547 (opens in a new tab)
Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.
https://doi.org/10.1016/j.ccell.2019.04.007 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Masayuki YamamotoTohoku Medical Megabank OrganizationJapanConstruction of Japanese whole genome database2019-06-24 – 2022-04-15
Teruhisa HochinFaculty of Information and Human Sciences, Kyoto Institute of TechnologyJapanAnalysis of mutation of human genome using Machine Learning2019-07-09 – 2022-03-23
Kouya ShiraishiDivision of Genome Biology, National Cancer Research InstituteJapanElucidation of immune-system networks between host and tumor based on genomic analysis2019-08-05 – 2029-03-31
Osamu OgasawaraBioinformation and DDBJ Center, National Institute of GeneticsJapanEvaluation of human genome analysis workflow using JGA/AGD genome data.2019-10-11 – 2024-07-05
Robert TsaiInstitute of Biosciences & Technology, Texas A&M Health Science CenterTexas, United StatesGenome-wide Discovery of new Plasma DNA Methylation Markers for Tracking the Progression of NAFLD to NASH and HCC2020-11-09 – 2023-07-25
Kichoon LeeUnited StatesAccess to the National Bioscience Database Center2021-05-31 – 2024-12-31
Jinyan HuangZhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, China. Biomedical big data center, the First Affiliated Hospital, Zhejiang UniversityChinaComprehensive analysis of alternative splicing in malignant tumors2022-03-15 – 2024-01-01
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31