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NBDC Research ID:hum0065-v1
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Title

Shuttle system between petient-derived xenograft and ex vivo culture for innovative platform of evaluating drug sensitivity

Research overview

Aims: This study aimed at establishment of CTOS (cancer tissue-originated spheroid) panel covering intra-patient heterogeneity for colorectal cancer, lung cancer and small cell carcinoma of the cervix. With the panel, changes in preparation, culture, and xenograft were pathologically, biochemically, and molecular biologically monitored.

Methods: Exome analysis by using Illumina HiSeq 2000

Targets: Colorectal cancer, Lung cancer, Small cell carcinoma of uterine cervix

Datasets

Dataset ID
Access type
Type of data
Release date
JGAD000089Controlled-access (Type I)NGS (Exome)2020-09-28

Data provider

    Representative
    Masahiro Inoue
    Organiation
    Department of Biochemistry, Osaka International Cancer Institute

Research projects

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Grants

Name
Title
Project number
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT), Japan Agency for Medical Research and Development (AMED)Development of an innovative drug evaluation system using a shuttle system between patient-derived tumors and an ex vivo assay
  • JP15cm0106155

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Controlled access users

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