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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0056-v1Release info

Latest

Research title

Genome and Multi-layer omics reference panels using blood samples from a population-based cohort study

Research overview

Aims
To provide genome and multi-layer omics data from a population based cohort (Iwate Medical Megabank: IMM) to research communities
Methods
Allele frequencies based on whole genome sequencing (WGS), methylation rates based on whole genome bisulfite sequencing (WGBS), and FPKM values based on RNA sequencing (RNA-seq) of 102 monocytes, 102 CD4+ T cells, and 94 neutrophils (total 197 individuals from IMM cohort) isolated from peripheral blood cells.
Participants/materials
Monocytes and CD4+ T cells from 102 individuals, and neutrophils from 94 individuals in each (total 197 individuals)
URL

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
NHA000067(1) Allele frequencies from WGS
  • WGS
Unrestricted-access2018-03-30
NHA000065(2) Methylation rates at each CpG site from WGBS
  • WGBS
Unrestricted-access2018-03-30
NHA000066(3) Average of FPKM values from RNA-seq
  • RNA-seq
Unrestricted-access2018-03-30

Data provider

Principal investigator
Atsushi Shimizu
Affiliation
Disaster Reconstruction Center, Iwate Medical University

Research projects

NameURL
Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization
N/A

Grants

NameTitleProject number
Japan Agency for Medical Research and Development (AMED)
Tohoku Medical Megabank Project (Iwate Medical University) Special Account of the Great East Japan Earthquake Disaster Recovery
  • JP18km0105003
Ministry of Education, Culture, Sports, Science and Technology Japan
Tohoku Medical Megabank Project
N/A

Related publications

TitleDOIDataset ID
Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies
https://doi.org/10.1038/s41525-017-0016-5 (opens in a new tab)
N/A