NBDC Research ID: hum0132.v1
SUMMARY
Aims: Identification of genetic alterations in Vietnamese individuals with elevated blood dioxin level
Methods: Whole genome sequencing by HiSeq 2500 (Illumina)
Participants/Materials: Nine trios of the father exposed to dioxin for a few years and his wife and child with mental retardation (total 27 individuals)
| Dataset ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| JGAS000137 | NGS (WGS) | Controlled-access (Type I) | 2018/09/07 |
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MOLECULAR DATA
| Participants/Materials | 9 trios of the father exposed to dioxin and his wife and child with mental retardation (total 27 individuals) |
| Targets | WGS |
| Target Loci for Capture Methods | - |
| Platform | Illumina [HiSeq 2500] |
| Library Source | DNAs extracted from peripheral blood cells |
| Cell Lines | - |
| Library Construction (kit name) | TruSeq Nano DNA Library Preparation Kit |
| Fragmentation Methods | Ultrasonic fragmentation (Covaris) |
| Spot Type | Paired-end |
| Read Length (without Barcodes, Adaptors, Primers, and Linkers) | 101 bp or 93 bp |
| Japanese Genotype-phenotype Archive Dataset ID | JGAD000206 |
| Total Data Volume | 1 TB (fastq) |
| Comments (Policies) | NBDC policy |
DATA PROVIDER
Principal Investigator: Hidewaki Nakagawa
Affiliation: Laboratory of Genome Sequencing Analysis, RIKEN Center for Integrative Medical Sciences
Project / Group Name: Vietnamese trio sequencing project
Funds / Grants (Research Project Number):
| Name | Title | Project Number |
|---|---|---|
| Scientific Program KHCN-33/11-15, the Ministry of Natural Resources and Environment (Vietnam) | Identification of genetic alterations in Vietnamese individuals with elevated blood dioxin level | Grant KHCN-33.06/11-15 |
| the Ministry of Science and Technology (Vietnam) | Identification of genetic alterations in Vietnamese individuals with elevated blood dioxin level | Grant DTDL.CN-05/15 |
PUBLICATIONS
| Title | DOI | Dataset ID | |
|---|---|---|---|
| 1 | Whole genome sequencing and mutation rate analysis of trios with paternal dioxin exposure. | doi: 10.1002/humu.23585 | JGAD000206 |
| 2 |
USRES (Controlled-access Data)
| Principal Investigator: | Affiliation: | Data in Use (Dataset ID) | Period of Data Use |
|---|---|---|---|
