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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD001065

Type of data
NGS (RNA-seq)
Access criteria
Controlled-access (Type I)
Total data volume
64.8 GB
File formats
  • BAM
Research
hum0210
Date published
2026-08-03
Date modified
2026-08-03
DDBJ Search
JGAD001065 (opens in a new tab)
JGA Study
JGAS000921 (opens in a new tab)

Analysis method

RNA-seq

Materials and participants
adult T-cell leukemia/lymphoma (ICD10: C91.5): 5 cases
tumour cells harvested from 5 ATL PDX models (one model per patient): 30 samples in total
- vehicle: 3 samples each
- MALT1 inhibitor CRD-1441551-treated: 3 samples each
  • Health status
    Affected
  • Subject count
    5 (Individual)
Disease
adult T-cell leukemia/lymphoma (C915)
Sample description
RNAs extracted from tumour cells harvested from PDX models
  • Tumor / normal
    Tumor
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Reagent kit
NEBNext Ultra RNA Library Prep Kit for Illumina
Fragmentation
included in the above library construction kit (chemical reaction, heat treatment)
Platform
MGI DNBSEQ-G400
Read type
Paired-end
Read length
150 bp
Reference genome
GRCh37
Mapping
STAR (v2.5.3a)
Mapping quality
Mouse-derived reads were removed from the PDX reads using Xenome, and only reads identified as human-derived were retained. The retained reads were aligned to UCSC hg19 with STAR (v2.5.3a) using default settings; default alignment filters removed reads with excessive mismatches, excessive multi-mapping, or insufficient aligned length. Only mapped reads are included (unmapped reads excluded).
Data use policy
NBDC data sharing policy (JGAP000001)