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Dataset ID

JGAD000870

Type of data
NGS (WGS, Exome, Amplicon-seq, RNA-seq, scRNA-seq/ADT-seq/TCR-seq, CUT&RUN-seq)
Methylation array
Access criteria
Controlled-access (Type I)
Total data volume
7.6 TB
File formats
  • FASTQ
  • BAM
  • BAI
  • IDAT
Research
hum0405
Date published
2026-08-07
Date modified
2026-08-07

Unrestricted-access files linked to this dataset

FileLabelSizeCopy URL
hum0405_TGS-probe-panel.xlsx399 genes20.5 KB
xgen-human-cnv-backbone-hyb-panel-probes.bedxGen CNV Backbone Panel-Tech Access (IDT)454 KB

Analysis method

WGS

Materials and participants
CAEBV (ICD10: C84.5): 18 cases
EBV-infected cells and uninfected cells: 36 samples
  • Health status
    Affected
  • Subject count
    18 (Individual)
Disease
CAEBV (C845)
Sample description
DNAs extracted from EBV-infected cells and uninfected cells
  • Tissue
    EBV-infected cell
Sample provider
N/A
Experimental method
WGS
Target
N/A
Reagent kit
Illumina DNA PCR-Free Prep
Lotus DNA Library Prep Kit
Fragmentation
Restriction enzyme reaction
on-bead tagmentation
Platform
Illumina NovaSeq 6000
MGI DNBSEQ-G400
Read type
Paired-end
Read length
150 bp
Reference genome
GRCh37
Mapping
Genomon v2.6.2
Mapping quality
N/A
Coverage (depth)
14 cases, tumor: 45x (More than)
14 cases, normal: 30x (More than)
4 cases, tumor: 100x (More than)
4 cases, normal: 30x (More than)

Exome

Materials and participants
CAEBV (ICD10: C84.5): 23 cases
EBV-infected cells and uninfected cells: 46 samples
  • Health status
    Affected
  • Subject count
    23 (Individual)
Disease
CAEBV (C845)
Sample description
DNAs extracted from EBV-infected cells and uninfected cells
  • Tissue
    EBV-infected cell
Sample provider
N/A
Experimental method
WES
Target
N/A
Reagent kit
Lotus DNA Library Prep Kit
xGen Exome Research Panel
Fragmentation
Restriction enzyme reaction
Platform
MGI DNBSEQ-G400
Read type
Paired-end
Read length
150 bp
Reference genome
GRCh37
Mapping
Genomon v2.6.2
Mapping quality
N/A
Coverage (depth)
Tumor: 100x (More than)
Normal: 100x (More than)

Amplicon-seq

Materials and participants
CAEBV (ICD10: C84.5): 64 cases
EBV-infected cells, uninfected cells and peripheral blood cells: 185 samples
  • Health status
    Affected
  • Subject count
    64 (Individual)
Disease
CAEBV (C845)
Sample description
DNAs extracted from EBV-infected cells, uninfected cells and peripheral blood cells
  • Tissue
    EBV-infected cell, Peripheral blood
Sample provider
N/A
Experimental method
Amplicon-seq
Target
1: 399 genes
2: xGen CNV Backbone Panel-Tech Access (IDT)
3: EBV type 1 (RefSeq accession number; NC_007605) and type 2 (RefSeq accession number; NC_009334)
Reagent kit
Lotus DNA Library Prep Kit
Fragmentation
Restriction enzyme reaction
Platform
MGI DNBSEQ-G400
Read type
Paired-end
Read length
150 bp
Reference genome
EBV type 1
GRCh37
Mapping
Genomon v2.6.2
Mapping quality
N/A
Coverage (depth)
399 genes: 1000x

RNA-seq

Materials and participants
CAEBV (ICD10: C84.5): 28 cases
EBV-infected cells and cell-lines
IM (ICD10: B27.0, B27.9): 6 cases
NK cells
4 healthy individuals
NK cells
52 samples in total
  • Health status
    Mixed
  • Subject count
    38 (Individual)
Disease
CAEBV (C845)
IM (B270, B279)
Sample description
RNAs extracted from EBV-infected cells, cell-lines and NK cells
  • Tissue
    Cell line, EBV-infected cell, NK cell
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Reagent kit
NEBNext rRNA Depletion Kit
NEBNext Ultra II Directional RNA Library Prep Kit for Illumina
Fragmentation
Heat treatment
Platform
MGI DNBSEQ-G400
Read type
Paired-end
Read length
150 bp
Reference genome
EBV type 1
GRCh37
Mapping
Genomon v2.6.2
Mapping quality
N/A

Methylation Array

Materials and participants
CAEBV (ICD10: C84.5): 32 cases
EBV-infected cells and cell-lines
IM (ICD10: B27.0, B27.9): 6 cases
NK cells
4 healthy individuals
NK cells
54 samples in total
  • Health status
    Mixed
  • Subject count
    42 (Individual)
Disease
CAEBV (C845)
IM (B270, B279)
Sample description
DNAs extracted from EBV-infected cells, cell-lines and NK cells
  • Tissue
    Cell line, EBV-infected cell, NK cell
Sample provider
N/A
Experimental method
Methylation array
Target
N/A
Reagent kit
Infinium MethylationEPIC BeadChip Kit
Platform
Illumina Infinium MethylationEPIC
Probe count
N/A

scRNA-seq/ADT-seq/TCR-seq

Materials and participants
CAEBV (ICD10: C84.5): 6 cases
IM (ICD10: B27.0, B27.9): 2 cases
2 healthy individuals
peripheral blood mononuclear cells (PBMC): 10 samples in total
  • Health status
    Mixed
  • Subject count
    10 (Individual)
Disease
CAEBV (C845)
IM (B270, B279)
Sample description
RNAs extracted from PBMCs
  • Tissue
    PBMC, Peripheral blood
Sample provider
N/A
Experimental method
scRNA-seq
TCR-seq
Target
N/A
Reagent kit
Chromium Next GEM Single Cell 5' v2
Chromium Single Cell V(D)J
Fragmentation
Restriction enzyme reaction
Platform
MGI DNBSEQ-G400
Read type
Paired-end
Read length
100 bp

CUT&RUN-seq

Materials and participants
CAEBV (ICD10: C84.5): 2 cases
cell-lines
1 healthy individual
NK cells
24 samples in total
  • Health status
    Mixed
  • Subject count
    3 (Individual)
Disease
CAEBV (C845)
Sample description
DNAs extracted from cell-lines and NK cells
  • Tissue
    Cell line, NK cell
Sample provider
N/A
Experimental method
CUT&RUN-seq
Target
N/A
Reagent kit
CUTANA ChIC/CUT&RUN Kit Version 3
NEBNext Ultra II DNA Library Prep Kit for Illumina
Fragmentation
Restriction enzyme reaction
Platform
MGI DNBSEQ-G400
Read type
Paired-end
Read length
150 bp
Reference genome
GRCh37
Mapping
CUT&RUNTools 2.0 package
Mapping quality
N/A