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Dataset ID

JGAD000790

Type of data
NGS (RNA-seq)
Access criteria
Controlled-access (Type I)
Total data volume
180 GB
File formats
  • FASTQ
Research
hum0433
Date published
2024-09-26
Date modified
2025-08-26

Analysis method

RNA-seq

Materials and participants
hypertensive disorders of pregnancy (ICD10: O149): 10 cases
trophoblast stem cells derived from placenta after delivery
3 cases; 3 samples (hTSC, EVT, ST) each
7 cases; 1 sample (ST) each
10 cases; 1 sample (hypoxia-treated hTSCs) each
normal pregnancy: 11 subjects
trophoblast stem cells derived from placenta after delivery
3 cases; 3 samples (hTSC, EVT, ST) each
8 cases; 1 sample (ST) each
11 cases; 1 sample (hypoxia-treated hTSCs) each
  • Health status
    Mixed
  • Subject count
    21 (Individual)
  • Sex
    Female
Disease
hypertensive disorders of pregnancy (O149)
Sample description
RNAs extracted from trophoblast stem cells and CT cells
  • Tissue
    Decidua, Placenta, Trophoblast stem cell
  • Tumor / normal
    Normal
Cell line
Extravillous trophoblast (EVT)
Syncytiotrophoblast (ST)
Trophoblast stem cell (TS)
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Reagent kit
NEBNext Ultra II Directional RNA Library Prep Kit for Illumina
Fragmentation
included in the above library construction kit
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp