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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD000531

Type of data
target sequencings of 27 cancer-predisposing genes and 13 renal cell carcinoma-related genes in 740 renal cell cancer patients and 5,996 controls
Access criteria
Controlled-access (Type I)
Total data volume
962 GB
File formats
  • FASTQ
Research
hum0014
Date published
2022-04-07
Date modified
2022-04-07
DDBJ Search
JGAD000531 (opens in a new tab)
JGA Study
JGAS000414 (opens in a new tab)

Analysis method

Targeted DNA sequencing

Materials and participants
1,005 pancreatic cancer patients (ICD10: C25)
12,503 colorectal cancer patients (ICD10: C18, C19, C20)
740 renal cell cancer patients (ICD10: C64)
1,982 lymphoma patients (ICD10: C81, C82, C83, C84, C85, C86, C88, C91)
10,366 gastric cancer patients (ICD10: C16)
23,705 + 5,996 + 37,592 controls
renal cell cancer and 5,996 controls
  • Health status
    Mixed
  • Subject count
    93,889 (Individual)
Disease
  • pancreatic cancer patients
  • colorectal cancer patients
  • renal cell cancer patients
  • lymphoma patients
  • gastric cancer patients
Sample description
DNA extracted from peripheral blood cells
  • Tissue
    Peripheral blood
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
Targeted DNA sequencing
Target
27 cancer-predisposing genes (APC, ATM, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDK4, CDKN2A, CDH1, CHEK2, EPCAM, HOXB13, NBN, NF1, MLH1, MSH2, MSH6, MUTYH, PALB2, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53)
Reagent kit
KAPA HiFi DNA Polymerase
2X Platinum Multiplex PCR Master Mix
Fragmentation
N/A
Platform
Illumina HiSeq 2500
Read type
Paired-end
Read length
150 bp
Data use policy
NBDC data sharing policy (JGAP000001)

Targeted DNA sequencing

Materials and participants
740 renal cell cancer patients (ICD10: C64)
5,996 controls
  • Health status
    Mixed
  • Subject count
    6736 (Individual)
Disease
  • renal cell cancer patients
Sample description
DNA extracted from peripheral blood cells
  • Tissue
    Peripheral blood
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
Targeted DNA sequencing
Target
13 renal cell carcinoma-related genes (VHL, BAP1, FH, FLCN, MET, TSC1, TSC2, MITF, SDHA, SDHB, SDHC, SDHD, CDC73)
Reagent kit
KAPA HiFi DNA Polymerase
2X Platinum Multiplex PCR Master Mix
Fragmentation
N/A
Platform
Illumina HiSeq 2500
Read type
Paired-end
Read length
150 bp
Data use policy
NBDC data sharing policy (JGAP000001)