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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD000497

Type of data
NGS (RNA-seq)
Access criteria
Controlled-access (Type I)
Total data volume
45.6 GB
File formats
  • FASTQ
Research
hum0302
Date published
2021-11-10
Date modified
2021-11-10
DDBJ Search
JGAD000497 (opens in a new tab)
JGA Study
JGAS000382 (opens in a new tab)

Analysis method

RNA-seq

Materials and participants
Five samples of hepatocytes differentiated from iPS cells derived from patients with Wilson's disease (ICD10: E830)
One hepatocyte sample from a patient with Wilson's disease in which the ATP7B mutation was corrected by genome editing of iPS cells
Five samples of hepatocytes differentiated from healthy human-derived iPS cells
One hepatocyte sample in which the ATP7B mutation was introduced by genome editing of healthy donor-derived iPS cells
[Total: 12 samples]
  • Health status
    Mixed
  • Subject count
    30 (Sample)
Disease
Wilson's disease (E830)
Sample description
RNAs extracted from hepatocytes and kidney organoids differentiated from iPS cells
  • Tissue
    Hepatocyte, Kidney organoid
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
RNA-seq
Target
N/A
Fragmentation
GeneWiz inc.'s protocol
Platform
Illumina NovaSeq 6000
Read type
Paired-end
Read length
150 bp
Data use policy
NBDC data sharing policy (JGAP000001)