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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD000452

Type of data
Genotypes for 1,193 Japanese individuals vaccinated with a HB vaccine (Bimmugen)
Access criteria
Controlled-access (Type I)
Total data volume
34.4 GB
File formats
  • CEL
  • CSV
Research
hum0136
Date published
2021-09-28
Date modified
2021-09-28
DDBJ Search
JGAD000452 (opens in a new tab)
JGA Study
JGAS000341 (opens in a new tab)

Analysis method

Genotyping by array

Materials and participants
1,193 Japanese individuals vaccinated with a HB vaccine (Bimmugen)
- Low responders (n=107, HBsAb ≤ 10mIU/mL)
- Intermediate responders (n=351, 10mIU/mL < HBsAb ≤ 100mIU/mL)
- High responders (n=735, HBsAb >100mIU/mL)
864 Japanese individuals under the age of 30 years vaccinated with a HB vaccine (Bimmugen)
- Low responders (n=56, HBsAb ≤ 10mIU/mL)
- Intermediate responders (n=226, 10mIU/mL < HBsAb ≤ 100mIU/mL)
- High responders (n=582, HBsAb >100mIU/mL)
  • Health status
    Healthy
  • Subject count
    1193 (Individual)
  • Population
    Japanese
Sample description
DNAs extracted from peripheral blood cells
  • Tissue
    Peripheral blood
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
Genotyping by array
Target
N/A
Platform
Affymetrix Axiom Genome-Wide ASI 1 Array
Reference genome
GRCh37
QC and filtering
overall call rate < 0.95, SNP call rate < 0.95,
HWE P < 0.001, MAF < 0.05, Regression P < 0.05
Analysis method
GenCall software (Genotyping Console ver. 4.2.0.26)
Variant count
I. Regression analysis for low (0), intermediate (1), and high (2) responders (covariates: age and gender): 22,044 SNPs (Figure 2)
II. Regression analysis for low (0), intermediate (1), and high (2) responders under the age of 30 years (covariates: age and gender): 21,580 SNPs (Supplementary Figure 4)
III. Regression analysis for low (0) and high (1) responders (covariates: age and gender): 23,765 SNPs (Supplementary Figure 5)
Phenotype data
Included
Data use policy
NBDC data sharing policy (JGAP000001)