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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

JGAD000137

Type of data
GWAS for NAFLD, NASH, and NASH-HCC
Access criteria
Controlled-access (Type I)
Total data volume
14.1 MB
File formats
  • XLSX
Research
hum0119
Date published
2020-09-28
Date modified
2021-04-20
DDBJ Search
JGAD000137 (opens in a new tab)
JGA Study
JGAS000126 (opens in a new tab)

Analysis method

Genotyping by array

Materials and participants
NAFLD (ICD10: K76.0): 264 patients
NASH (ICD10: K75.81): 580 patients
NASH-HCC (ICD10: C220): 58 patients
7672 healthy controls
  • Health status
    Mixed
  • Subject count
    8574 (Individual)
Disease
NAFLD (K760)
NASH (K758)
NASH-HCC (C220)
Sample description
DNAs extracted from peripheral blood cells
  • Tissue
    Peripheral blood
  • Tumor / normal
    Mixed
Sample provider
N/A
Experimental method
Genotyping by array
Target
N/A
Reagent kit
Human610-Quad BeadChip Kit
HumanCoreExome BeadChip Kit
HumanOmni2.5 BeadChip Kit
Platform
Illumina Human610-Quad
Illumina HumanCoreExome
Illumina HumanOmni2.5
Reference genome
GRCh37
QC and filtering
Exclusion criteria : sample call-rate < 0.95, PCA outlier of Japanese population, encrypted relatedness (pihat > 0.38)
SNP call-rate < 0.99, HWE-p < 1e-6, MAF< 0.01
Analysis method
GenomeStudio (Illumina)
Variant count
93,606 SNPs
Phenotype data
Included
Data use policy
NBDC data sharing policy (JGAP000001)