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Dataset ID

JGAD000120

Type of data
Methylation array
Access criteria
Controlled-access (Type I)
Total data volume
439 MB
File formats
  • TXT
Research
hum0108
Date published
2020-09-28
Date modified
2020-11-18

Analysis method

メチル化アレイ

Materials and participants
Panic disorder (ICD10: F410) : 48 cases
Healthy controls: 48 samples
(including a pair of discordant monozygotic twins)
  • Health status
    Mixed
  • Subject count
    96 (Individual)
Disease
Panic disorder (F410)
Sample description
DNAs extracted from peripheral blood cells
  • Tissue
    Peripheral blood
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
Methylation array
Target
N/A
Reagent kit
EZ DNA Methylation Kit
Infinium HumanMethylation450 BeadChip Kit
Platform
Illumina Infinium HumanMethylation450
Reference genome
GRCh37
QC and filtering
(1) detection p value of each probe ≥ 0.01
(2) probe call rate >95%
(3) on autosomal chromosomes
(4) does not include SNP which minor allele frequency is greater than or equal to 5%
(5) hybridizes to a specific sequence*1
Normalization
(1) Lumi: quantile normalizationbeta mixture quantile*2
(2) BMIQ normalization*3
(3) ComBat*4
Analysis method
iScan system and GenomeStudio Software
Probe count
376,602 (methylation sites)