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NBDC Human Database

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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0505-v1Release info

Latest

Research title

Exploratory study of genetic factors in allergic diseases

Research overview

Aims
Genetic factors play an important role for the development of allergic diseases such as bronchial asthma, hay fever, atopic dermatitis, and food allergy. This study aims to identify genes involved in the pathogenesis of allergic diseases.
Methods
DNA was extracted from blood or saliva and genotyped using the Infinium Asian Screening Array (illumina).
Participants/materials
Five hundred and sixty-four children who participated in T-Child study (a birth cohort study) with ImmunoCAP ISAC sIgE 112 data available at age 9 years.
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
NHA000201GWAS for 564 children who participated in the adult cohort study
  • Genotyping by array (GWAS)
Unrestricted-access2025-05-30

Data provider

Principal investigator
Emiko Noguchi
Affiliation
Faculty of Medicine, Department of Medical Genetics, University of Tsukuba

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (B)
Elucidation of Genetic and Environmental Factors in Allergic Disease using Birth Cohort Study
  • 16H03269
Practical Research Project for Allergic Diseases and Immunology, Japan Agency for Medical Research and Development (AMED)
Development of a prediction method for allergic diseases and allergen responsiveness using patients cohorts and general population cohorts
  • JP20ek0410076
National Center for Child Health and Development (NCCHD)
A birth cohort study on the establishment of long-term follow-up data with genetic information and the elucidation of disease etiology in perinatal and pediatric medicine
  • 26-18

Related publications

TitleDOIDataset ID
A genome-wide association study for allergen component sensitizations identifies allergen component-specific and allergen protein group-specific associations