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NBDC Human Database

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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0493-v1Release info

Latest

Research title

Functional analysis of skin immunocompetent cells

Research overview

Aims
Examine the interaction between the cells responsible for skin immunity and the stromal cells that maintain the structure of the skin. Then analyse their function.
Methods
10x Xenium spatial transcriptome
Participants/materials
Healthy skin from 3 individuals
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000913Xenium In Situ Gene Expression
  • Xenium 空間トランスクリプトーム
Controlled-access (Type I)2025-07-25

Data provider

Principal investigator
Hanako Koguchi-Yoshioka
Affiliation
Department of Neurocutaneous Medicine, the University of Osaka

Research projects

No research projects.

Grants

NameTitleProject number
Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED)
Elucidation of immunosenescence mechanisms associated with reduced plasticity of resident memory T cells
  • JP23gm6710019
KAKENHI Grant-in-Aid for Scientific Research (B)
Investigating how pathogenic resident memory T cells are established and maintained in chronic inflammatory skin conditions
  • 24K02472
JSID's Fellowship Shiseido Research Grant
Preventive strategies for malignant tumor development associated with age-related changes in the skin microenvironment
N/A
Nakatomi Foundation
Investigation of dynamic changes in the interaction between the aging skin microenvironment and T cells
N/A
The Lydia O'Reilly Memorial Foundation for the Promotion of Dermatology
Investigation of the correlation between age-related changes in the skin microenvironment and the development of cutaneous malignancies
N/A
Takeda Science Foundation
Elucidation of the mechanisms underlying the establishment and functional maintenance of skin-resident memory T cells centered on the skin microenvironment
N/A

Related publications

TitleDOIDataset ID
Immunoregulatory microenvironment in the elderly skin

Controlled access users

No use of the controlled access data has been recorded.