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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0447-v1Release info

Latest

Research title

Comprehensive genomic analysis to elucidate the molecular mechanism of initiation and progression of liver cancer, pancreatic cancer, lung cancer, stomach cancer, colorectal cancer, biliary tract cancer, breast cancer, esophageal cancer, uterine cancer, ovarian cancer, bladder cancer, kidney cancer, head and neck cancer, bone and soft tissue sarcoma, and malignant melanoma.

Research overview

Aims
Intractable cancers (pancreatic, lung, colorectal, ovarian, uterine, esophageal, breast, bladder, kidney, and head and neck cancers; bone and soft tissue sarcoma; and malignant melanoma), as well as cancers that are more common in Japan (gastric, liver, and biliary tract cancers), were targeted. To clarify the onco-genomic landscape in relation to pathological conditions, we are conducting comprehensive, exploratory genomic analyses with the following aims: 1. To clarify genomic abnormalities. 2. To identify correlations between genomic abnormalities and malignant phenotypes of tumors (e.g., metastasis and invasion) that affect responses to various therapies and prognosis. 3. To establish new effective treatments and diagnostic methods.
Methods
Whole Genome sequencing
Participants/materials
Colorectal tumor tissues and peripheral blood cells from 138 Japanese colorectal cancer patients
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000829NGS (WGS)
  • WGS
Controlled-access (Type I)2026-06-10

Data provider

Principal investigator
Tatsuhiro Shibata
Affiliation
Division of Cancer Genomics, National Cancer Center Research Institute

Research projects

No research projects.

Grants

NameTitleProject number
Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)
Establishment of a Large-Scale Integrated Japanese Cancer Genome, Multi-Omics, and Clinical Data Resource for International Collaborative Research, Genome-Based Prevention, and Precision Medicine.
  • JP25ck0106800

Related publications

TitleDOIDataset ID
Prevalence and chronology of colibactin-associated mutational processes and their microbiome spectra in Japanese colorectal cancer
https://doi.org/10.52843/cassyni.86lmq6 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.