Skip to content
NBDC Human Database

No datasets in the cart.

Go to the cart

Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0385-v1Release info

This page is a past version (v1). The latest version is v2.
Latest version (v2)

Research title

Comprehensive genetic analysis of Combined hepatocellular-cholangiocarcinoma, Cholangiolocarcinoma, Keratin 19-expressing hepatocellular carcinoma, and SOX9-expressing hepatocellular carcinoma

Research overview

Aims
To investigate genetic mutations of Combined hepatocellular-cholangiocarcinoma, Cholangiolocarcinoma, Keratin 19-expressing hepatocellular carcinoma, and SOX9-expressing hepatocellular carcinoma and to clarify their association with clinicopathological features
Methods
We obtained non-tumor and tumor tissues from surgical specimens of cholangiolocarcinoma and combined hepatocellular-cholangiocarcinoma and extracted DNA from tissues, then performed whole-exome sequencing analysis.
Participants/materials
Cholangiolocarcinoma and combined hepatocellular-cholangiocarcinoma patients
URL
N/A

Datasets

The list is the one this version published; each dataset's content is shown as it is now.

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000726NGS (Exome)
  • WES
Controlled-access (Type I)2023-12-13

Data provider

Principal investigator
Takamichi Ishii
Affiliation
Department of Surgery, Graduate School of Medicine, Kyoto University

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (C)
Elucidation of Genomic Heterogeneity in Hepatocellular Carcinoma from the Perspective of Cancer Stem Cells
  • 19K09145

Related publications

TitleDOIDataset ID
Integrated analyses of the genetic and clinicopathological features of cholangiolocarcinoma: cholangiolocarcinoma may be characterized by mismatch-repair deficiency.
https://doi.org/10.1002/path.6257 (opens in a new tab)
Comprehensive analyses of the clinicopathological features and genomic mutations of combined hepatocellular-cholangiocarcinoma
https://doi.org/10.1111/hepr.13965 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.