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NBDC Human Database

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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0345-v1Release info

Latest

Research title

Fundamental study for regenerative medicine utilizing cord blood

Research overview

Aims
To clarify the differentiation pathway and mechanism of human lymphoid and dendritic cells from hematopoietic stem cells
Methods
CD34+ cells or target cells in CD34+ cells were sorted and assessed for scRNA-seq and ATAC-seq analyses. Obtained findings were evaluated by culture on a co-culture system.
Participants/materials
Cord blood (30-50ml) was obtained from healthy volunteers and kept in a freezer after the selection of CD34+ cells. Mixtures of several samples were used for experiments.
- One mixed sample (CD34+) of 2 volunteers' cord blood
- One mixed sample (CD10SP) of 30 volunteers' cord blood
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000647NGS (scRNA-seq)
NGS (ATAC-seq)
  • scRNA-seq
  • ATAC-seq
Controlled-access (Type I)2022-08-09
JGAD000671NGS (scRNA-seq)
  • scRNA-seq
Controlled-access (Type I)2022-08-09

Data provider

Principal investigator
Kohshi Ohishi
Affiliation
Transfusion Medicine and Cell Therapy, Mie University Hospital

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (C)
Study of human lymphopoiesis and neoplastic transformation with novel culture system
  • 18K08322
KAKENHI Grant-in-Aid for Scientific Research on Innovative Areas
Platform for Advanced Genome Science
  • 16H06279

Related publications

No related publications.

Controlled access users

No use of the controlled access data has been recorded.