Research ID
hum0270-v1Release info
Research title
Translational research for elucidating molecular and pathological abnormalities specific to bone and soft tissue tumors based on genomic and genetic analysis, and for developing new diagnostic and therapeutic strategies
Research overview
- Aims
- To identify prognosis-related genomic alterations in pediatric Osteosarcoma patients using NGS technique.
- Methods
- By using a comprehensive cancer panel which amplifies coding exons of cancer-related 409 genes, candidate mutations occurred in OS were surveyed.
- Participants/materials
- Pediatric Osteosarcoma: 16 patients
- URL
- N/A
Datasets
| Cart | Dataset ID | Type of data | Analysis method | Access criteria | Date published |
|---|---|---|---|---|---|
| JGAD000388 | NGS (Target Capture) |
| Controlled-access (Type I) | 2021-04-05 |
Data provider
- Principal investigator
- Tsukasa Yonemoto
- Affiliation
- Division of Orthopedic Surgery, Chiba Cancer Center
Research projects
No research projects.
Grants
| Name | Title | Project number |
|---|---|---|
KAKENHI Grant-in-Aid for Young Scientists (B) | Molecular profiling to predict chemosensitivity for osteosarcoma |
|
KAKENHI Grant-in-Aid for Scientific Research (C) | Analysis of factors determining chemosensitivity and pulmonary metastasis in patients with osteosarcoma by genomic expression analysis |
|
Grants-in-Aid by the Ministry of Health, Labor and Welfare of Japan for the Third Term Comprehensive 10-year Strategy for Cancer Control | Genomic and gene expression profiling of pediatric solid tumors |
|
Related publications
| Title | DOI | Dataset ID |
|---|---|---|
CDK4 overexpression is a predictive biomarker for resistance to conventional chemotherapy in patients with osteosarcoma |
Controlled access users
No use of the controlled access data has been recorded.