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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0217-v1Release info

Latest

Research title

Identification of genetic alterations predicting cancer progression from colorectal polyps

Research overview

Aims
To clarify molecular and clinicopathological characteristics of colorectal serrated lesions
Methods
Targeted capture sequencing analysis of 39 genes mutated in colorectal cancers and/or serrated lesions
Participants/materials
50 serrated lesions, including TSAs, SSAs and microvesicular hyperplastic polyps
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000303NGS (Target Capture)
  • Targeted DNA sequencing
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Takeshi Sawada
Affiliation
Division of Translational and Clinical Oncology, Cancer Research Institute, Kanazawa University

Research projects

No research projects.

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (C)
Molecular analysis of traditional serrated adenoma as a candidate precursor of alternative serrated pathway
  • 16K09304
KAKENHI Grant-in-Aid for Scientific Research on Priority Areas (Research in a proposed research area)
Platform for Advanced Genome Science
  • 16H06279
Grant-in-Aid from the Takeda Science Foundation
Identification of carcinogenic pathway from serrated precursor lesions to poor-prognosis colon cancer
N/A
Grant-in-Aid from the Japanese Foundation for Research and Promotion of Endoscopy
Identification of carcinogenic mechanism of colorectal traditional serrated adenoma and application for endoscopic treatment
N/A
Collaborative Research Grant of Cancer Research Institute, Kanazawa University
Molecular analysis of alternative serrated pathway originating from colorectal traditional serrated adenoma
N/A

Related publications

TitleDOIDataset ID
Significance of gene mutations in the Wnt signaling pathway in traditional serrated adenomas of the colon and rectum
https://doi.org/10.1371/journal.pone.0229262 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.