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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0169-v2Release info

Latest

Research title

Molecular analysis to identify novel biomarker and therapeutic target for cerebrospinal tumor and preclinical investigation using patient derived orthotopic xenograft models.

Research overview

Aims
to compare genomic alterations between tumor tissues from Primary Central Nervous System Lymphoma (PCNSL) patients and xenograft samples derived from PCNSL patients
Methods
whole exome sequencing
Participants/materials
Nine samples, including patient derived xenograft (PDX) mice, tumor samples and peripheral blood cells from PCNSL patients
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000259NGS (Exome)
  • WES
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Tetsuya Yamamoto
Affiliation
Department of Neurosurgery, Yokohama City University

Research projects

NameURL
Neurosurgical-Oncology lab, Yokohama City University
N/A

Grants

NameTitleProject number
KAKENHI Grant-in-Aid for Scientific Research (C)
Development of novel therapeutic target for IDH mutant gliomas with DNA hypermutation
  • 19K09488

Related publications

TitleDOIDataset ID
A Rapid Genotyping Panel for Detection of Primary Central Nervous System Lymphoma
https://doi.org/10.1182/blood.2020010137 (opens in a new tab)
A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma
https://doi.org/10.1158/0008-5472.can-20-2425 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.