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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0113-v1Release info

This page is a past version (v1). The latest version is v3.
Latest version (v3)

Research title

Development of metabolite biomarkers of Parkinson's disease and identification of drug seeds from chemical screening based on the biomarkers

Research overview

Aims
Identification of RNA biomarkers in Parkinson's disease (PD) patients
Methods
Transcriptome sequencing (CAGE-seq)
Participants/materials
Whole blood samples from 39 PD patients and 20 non-PD (healthy) controls
iPS-derived neuron cells provided by 2 PD patients with PARK2 mutations and 3 non-PD (healthy) controls
iPS-derived neuronal stem cells (NSC) provided by 2 PD patients with PARK2 mutations and 3 non-PD (healthy) controls
URL
N/A

Datasets

The list is the one this version published; each dataset's content is shown as it is now.

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000129NGS (CAGE-seq)
  • CAGE-seq
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Piero Carninci
Affiliation
RIKEN Center for Integrative Medicine Science, Division of Genomic Medicine

Research projects

No research projects.

Grants

NameTitleProject number
Core Research and Evolutional Science and Technology, Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-CREST)
Development of metabolite biomarker specific for Parkinson's disease and identification of drug seeds based on its molecular target
  • JP19gm0710011

Related publications

TitleDOIDataset ID
Multi-year whole-blood transcriptome data for the study of onset and progression of Parkinson's Disease
https://doi.org/10.1038/s41597-019-0022-9 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.