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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
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Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0042-v1Release info

Latest

Research title

Genome analysis for elucidation of genetic factors in orofacial traits and diseases

Research overview

Aims
To identify susceptibility genes associated with degenerative bony changes of the temporomandibular joint (TMJ) and third molar agenesis.
Methods
Illumina HumanOmniExpress BeadChip was used for genotyping.
Participants/materials
(1) 146 cases with TMJ and 374 controls (non-TMJ) in the Japanese and Korean populations
(2) 149 cases with at least one-third molar agenesis and 338 controls in the Japanese and Korean populations
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
NHA000048GWAS in TMJ (105 Japanese cases, 41 Korean cases) and
non-TMJ (193 Japanese controls, 181 Korean controls)
  • Genotyping by array (GWAS)
Controlled-access (Type I)2016-03-02
NHA000047mandibular third molar agenesis (40 Japanese cases, 40 Korean cases),
maxillary third molar agenesis (62 Japanese cases, 63 Korean cases),
at least one-third molar agenesis (78 Japanese cases, 71 Korean cases)
  • Genotyping by array (GWAS)
Controlled-access (Type I)2016-03-02

Data provider

Principal investigator
Tetsutarou Yamaguchi
Affiliation
Showa University School of Dentistry

Research projects

No research projects.

Grants

NameTitleProject number
Ministry of Education, Culture, Sports, Science and Technology (MEXT) KAKENHI Grant-in-Aid for Scientific Research on Innovative Areas
Genome Science
  • 221S0002

Related publications

TitleDOIDataset ID
Genome-wide association study of degenerative bony changes of the temporomandibular joint.
https://doi.org/10.1111/odi.12141 (opens in a new tab)
A genome-wide association study of third molar agenesis in Japanese and Korean populations.
https://doi.org/10.1038/jhg.2013.106 (opens in a new tab)

Controlled access users

No use of the controlled access data has been recorded.