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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0022-v1Release info

Latest

Research title

Analysis of the Molecular Mechanism for Developing Donor-Origin Leukemia after Allogeneic Stem Cell Transplantation.

Research overview

Aims
To clarify the molecular mechanism underlying malignant transformation of Donor-cell derived leukemia (DCL).
Methods
Whole Exome Sequencing was performed by using of Illumina HiSeq 2000.
Participants/materials
One DCL patient and one donor
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000017NGS (Exome)
  • WES
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Hitoshi Kiyoi
Affiliation
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine

Research projects

NameURL
Project for Development of Innovative Research on Cancer Therapeutics , Team for Strategic Therapy Design
N/A

Grants

NameTitleProject number
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT)
Therapy 1 : Establishment of the strategic therapy design based on the development of molecular-targeted drugs / Therapy 1 - ① : Establishment of the optimal remedy based on the leukemia genome study
N/A

Related publications

TitleDOIDataset ID
Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation
https://doi.org/10.1038/leu.2013.278 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Seishi OgawaDepartment of Pathology and Tumor biology, Kyoto UniversityJapanThe comprehensive analysis of gene mutations in the patients with myeloid neoplasms.2015-12-21 – 2016-03-22