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Due to system maintenance, the application system, application review by the Data Access Committee will be unavailable during the following period.
Schedule: October 5th (Mon), 2026, 9:00 - October 7th (Wed), 2026, 15:00 (JST)
We apologize for any inconvenience this may cause and appreciate your understanding.

We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Research ID

hum0007-v1Release info

Latest

Research title

Gene Expression of Human Th17 Cells Before and After Activation

Research overview

Aims
To clarify the mechanism of auto-immune diseases and establish the treatment for auto-immune diseases, through analyzing the expression pattarns of Th1 cells and Th17 cells.
Methods
RNA-Seq by using of AppliedBioSystem SoLiD system
Participants/materials
Total RNAs were extracted from naïve T cells, CXCR3+Th1 cells, CD161+Th17 cells, and activated Th17 cells for one individual
URL
N/A

Datasets

CartDataset IDType of dataAnalysis methodAccess criteriaDate published
JGAD000005NGS (RNA-seq)
  • RNA-seq
Controlled-access (Type I)2020-09-28

Data provider

Principal investigator
Sanju Iwamoto
Affiliation
Department of Biochemistry, Showa University School of Medicine

Research projects

Grants

No grants.

Related publications

TitleDOIDataset ID
TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses.
https://doi.org/10.4049/jimmunol.179.3.1449 (opens in a new tab)

Controlled access users

Principal investigatorAffiliationCountry/RegionResearch titlePeriod of data useDataset ID
Michiaki HamadaHamada Laboratory, Faculty of Science and Engineering, Waseda UniversityJapanConstruction of RNA-targeted Drug Discovery Database2023-01-05 – 2027-10-31